Adriana Salatino - postdoc (ARC GABA-AD)

Studies have suggested that Alzheimer's disease (AD) is related to changes in brain function that are present already at very early, pre-clinical stages of the disease. For example, recent functional neuroimaging studies have shown early alterations in brain connectivity, and that these alterations are most prominent in highly-connected cortical "hub areas". These hub areas are also those that are most affected by AD lesions. These findings support the view that AD pathology could, at least in part, result from an activity-dependent degeneration. Initial excessive neural firing in hub areas due to increased excitability or connectivity could lead to later neurodegeneration and disruption of connectivity. Very recently, studies conducted by Prof. JN Octave (UCL) have suggested that AD could be related to a decrease in the expression of the cellular Cl- ion extruder KCC2, leading to an increase in intracellular Cl- and, thereby, an inhibitory-to-excitatory shift of GABAA receptor activity. The aim of the present study is to test whether GABAergic neurotransmission is altered at early pre-clinical and pre-demential stages of AD as compared to matched healthy controls.

Group members

Publications

Brain Stimulation

Everything is (still) illuminated: Dual right cathodal-left anodal tDCS of PPC prevents fatigue on a visual detection task

2020

Sarasso P, Ninghetto M, Salatino A, Ronga I, Bongiardina A, Iarrobino I, Neppi-Modona M, Ricci R.

12(1):187-189

Consciousness and Cognition

As long as that is my hand, that willed action is mine: Timing of agency triggered by body ownership

2020

Burin D, Pyasik M, Ronga I, Cavallo M, Salatino A, Pia L.

58:186-192

Brain Stimulation

Anodal Transcranial Direct Current Stimulation of the motor cortex reduces chronic pain in Alcock canal syndrome

2020

Ricci R, Ghiggia A, La Rosa I, Milano A, Troni W, George MS, Borckardt JJ, Castelli L, Salatino A.

in press

Journal of the International Neuropsychological Society

Biased Visuospatial Attention in Cervical Dystonia

2020

Chillemi G, Formica C, Salatino A, Calamuneri A, Girlanda P, Morgante F, Milardi D, Terranova C, Cacciola A, Quartarone A, Ricci R.

24(1):22-32

Journal of Advanced Research

Comparing intensities and modalities within the sensory attenuation paradigm: Preliminary evidence

2020

Burin D, Battaglini A, Pia L, Falvo G, Palombella M, Salatino A.

8(6):649-653

Cognition

That is my hand! Therefore, that is my willed action: How body ownership acts upon conscious awareness of willed actions

2020

Burin D, Pyasik M, Salatino A, Pia L.

166:164-173

Progress in Neuro-Psychopharmacology & Biological Psychiatry

Investigating the link between drug-naive first episode psychoses (FEPs), weight gain abnormalities and brain structural damages: Relevance and implications for therapy

2020

Minichino A, Ando A, Francesconi M, Salatino A, Delle Chiaie R, Cadenhead K.

77:9-22

Frontiers in Psychology

Sexual Well-Being in Patients with Blepharospasm, Spasmodic Torticollis, and Hemifacial Spasm: A Pilot Study

2020

Perozzo P, Salatino A, Cerrato P, Ricci R.

1.327777778

Frontiers in Behavioral Neuroscience

Cognitive and Neurophysiological Effects of Non-invasive Brain Stimulation in Stroke Patients after Motor Rehabilitation

2020

DAgata F, Peila E, Cicerale A, Caglio MM, Caroppo P, Vighetti S, Piedimonte A, Minuto A, Campagnoli M, Salatino A, Molo MT, Mortara P, Pinessi L, Massazza G.

0.510416667

Psychiatry Research

Rorschach Performance Assessment System (R-PAS) and vulnerability to stress: A preliminary study on electrodermal activity during stress

2020

Giromini L, Ando A, Morese R, Salatino A, Di Girolamo M, Viglione DJ, Zennaro A.

246:166-172

Neuropsychologia

Effects of attentional and cognitive variables on unilateral spatial neglect

2020

Ricci R, Salatino A, Garbarini F, Ronga I, Genero R, Berti A, Neppi-Mòdona M.

92:158-166

Brain Research

Embodied simulation and ambiguous stimuli: The role of the mirror neuron system

2020

Ando A, Salatino A, Giromini L, Ricci R, Pignolo C, Cristofanelli S, Ferro L, Viglione DJ, Zennaro A.

1629:135-42

Functional Neurology

Dual task-related gait changes in patients with mild cognitive impairment

2020

Nascimbeni A, Caruso S, Salatino A, Carenza M, Rigano M, Raviolo A, Ricci R.

30(1):59-65

Gait Posture

Gait attentional load at different walking speeds

2020

Nascimbeni A, Minchillo M, Salatino A, Morabito U, Ricci R.

41(1):304-6

Frontiers in Psychology

Hunting for right and left parietal hot spots using single-pulse TMS: modulation of visuospatial perception during line bisection judgment in the healthy brain

2020

Salatino A, Poncini M, George MS, Ricci R.

1.068055556

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN