Emanuel van den Broeke - postdoc (FRC)
The main objective of my research is to study pain - or nociception- induced central nervous system plasticity. Currently, my studies are focused on characterizing changes in nociceptive pathways that lead or contribute to hyperalgesia, and I am, thereby, particularly interested in the phenomenon of "central sensitization"; the increase responsiveness of nociceptive neurons in the central nervous system that generates widespread hyperalgesia ("secondary hyperalgesia").
Group members
Publications
Clinical Neurophysiology
Improving the recording of pinprick-evoked brain potentials in the context of central sensitization: the use of robot-controlled mechanical pinprick stimulation and a stimulus evaluation task
2020
van den Broeke EN, de Hemptinne P, Mercken M, Torta DM, Lambert J, Mouraux A.
in press
European Journal of Pain
Within- and between-session reliability of secondary hyperalgesia induced by electrical high-frequency stimulation
2020
Cayrol T, Lebleu J, Mouraux A, Roussel N, Pitance L, van den Broeke E.
in press
Pain
A highly cognitive demanding working memory task may prevent the development of nociceptive hypersensitivity
2020
Torta DME, De Laurentis M, Eichin KN, Von Leupoldt A, van den Broeke EN, Vlaeyen J.
in press
Journal of Neurophysiology
Burst-like conditioning electrical stimulation is more efficacious than continuous stimulation for inducing secondary hyperalgesia in humans
2020
Gousset S, Mouraux A, van den Broeke EN.
123(1):323-328
Cortex
The focus of spatial attention during the induction of central sensitization can modulate the subsequent development of secondary hyperalgesia
2020
Filbrich L, van den Broeke E, Legrain V, Mouraux .
124:193-203
Journal of Neurophysiology
Heterosynaptic facilitation of mechanical nociceptive input is dependent on the frequency of conditioning stimulation
2020
van den Broeke EN, Gousset S, Bouvy J, Stouffs A, Lebrun L, van Neerven SGA, Mouraux A.
122(3):994-1001
Journal of Psychosomatic Research
Central sensitization in humans: Popular phrase or useful concept?
2020
van den Broeke EN, Van den Bergh O.
119:51-52
Journal of Neurophysiology
Central sensitization increases the pupil dilation elicited by mechanical pinprick stimulation
2020
van den Broeke EN, Hartgerink DM, Butler J, Lambert J, Mouraux A.
121(5):1621-1632
Pain Reports
No evidence of widespread mechanical pressure hyperalgesia after experimentally-induced central sensitization via skin nociceptors
2020
Cayrol T, Pitance L, Roussel N, Mouraux A, van den Broeke EN.
3(6): e691
F1000 Research
Central sensitization and pain hypersensitivity: some critical considerations
2020
van den Broeke EN.
PLoS One
High frequency electrical stimulation induces a long-lasting enhancement of event-related potentials but does not change the perception elicited by intra-epidermal electrical stimuli delivered to the area of increased mechanical pinprick sensitivity
2020
Manresa JB, Andersen OK, Mouraux A, van den Broeke EN.
13(9):e0203365
Journal of Physiology
Quickly-responding C-fiber nociceptors contribute to heat hypersensitivity in the area of secondary hyperalgesia
2020
Lenoir C, Plaghki L, Mouraux A, van den Broeke EN.
in press
Clinical Psychological Science
Central sensitization: explanation or phenomenon?
2020
van den Broeke EN, Torta DM, Van den Bergh O.
in press
Nature: Scientific Reports
No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part
2020
Torta D, Filbrich L, van den Broeke E, Legrain V.
8(1):5359
Clinical Neurophysiology
Event-related brain potentials elicited by high-speed cooling of the skin: a robust and non-painful method to assess the spinothalamic system in humans
2020
De Keyser R, van den Broeke E, Courtin A, Dufour A, Mouraux A.
129(5):1011-1019