Emanuel van den Broeke - postdoc (FRC)

The main objective of my research is to study pain - or nociception- induced central nervous system plasticity. Currently, my studies are focused on characterizing changes in nociceptive pathways that lead or contribute to hyperalgesia, and I am, thereby, particularly interested in the phenomenon of "central sensitization"; the increase responsiveness of nociceptive neurons in the central nervous system that generates widespread hyperalgesia ("secondary hyperalgesia").

Group members

Publications

Clinical Neurophysiology

Improving the recording of pinprick-evoked brain potentials in the context of central sensitization: the use of robot-controlled mechanical pinprick stimulation and a stimulus evaluation task

2020

van den Broeke EN, de Hemptinne P, Mercken M, Torta DM, Lambert J, Mouraux A.

in press

European Journal of Pain

Within- and between-session reliability of secondary hyperalgesia induced by electrical high-frequency stimulation

2020

Cayrol T, Lebleu J, Mouraux A, Roussel N, Pitance L, van den Broeke E.

in press

Pain

A highly cognitive demanding working memory task may prevent the development of nociceptive hypersensitivity

2020

Torta DME, De Laurentis M, Eichin KN, Von Leupoldt A, van den Broeke EN, Vlaeyen J.

in press

Journal of Neurophysiology

Burst-like conditioning electrical stimulation is more efficacious than continuous stimulation for inducing secondary hyperalgesia in humans

2020

Gousset S, Mouraux A, van den Broeke EN.

123(1):323-328

Cortex

The focus of spatial attention during the induction of central sensitization can modulate the subsequent development of secondary hyperalgesia

2020

Filbrich L, van den Broeke E, Legrain V, Mouraux .

124:193-203

Journal of Neurophysiology

Heterosynaptic facilitation of mechanical nociceptive input is dependent on the frequency of conditioning stimulation

2020

van den Broeke EN, Gousset S, Bouvy J, Stouffs A, Lebrun L, van Neerven SGA, Mouraux A.

122(3):994-1001

Journal of Psychosomatic Research

Central sensitization in humans: Popular phrase or useful concept?

2020

van den Broeke EN, Van den Bergh O.

119:51-52

Journal of Neurophysiology

Central sensitization increases the pupil dilation elicited by mechanical pinprick stimulation

2020

van den Broeke EN, Hartgerink DM, Butler J, Lambert J, Mouraux A.

121(5):1621-1632

Pain Reports

No evidence of widespread mechanical pressure hyperalgesia after experimentally-induced central sensitization via skin nociceptors

2020

Cayrol T, Pitance L, Roussel N, Mouraux A, van den Broeke EN.

3(6): e691

F1000 Research

Central sensitization and pain hypersensitivity: some critical considerations

2020

van den Broeke EN.

PLoS One

High frequency electrical stimulation induces a long-lasting enhancement of event-related potentials but does not change the perception elicited by intra-epidermal electrical stimuli delivered to the area of increased mechanical pinprick sensitivity

2020

Manresa JB, Andersen OK, Mouraux A, van den Broeke EN.

13(9):e0203365

Journal of Physiology

Quickly-responding C-fiber nociceptors contribute to heat hypersensitivity in the area of secondary hyperalgesia

2020

Lenoir C, Plaghki L, Mouraux A, van den Broeke EN.

in press

Clinical Psychological Science

Central sensitization: explanation or phenomenon?

2020

van den Broeke EN, Torta DM, Van den Bergh O.

in press

Nature: Scientific Reports

No perceptual prioritization of non-nociceptive vibrotactile and visual stimuli presented on a sensitized body part

2020

Torta D, Filbrich L, van den Broeke E, Legrain V.

8(1):5359

Clinical Neurophysiology

Event-related brain potentials elicited by high-speed cooling of the skin: a robust and non-painful method to assess the spinothalamic system in humans

2020

De Keyser R, van den Broeke E, Courtin A, Dufour A, Mouraux A.

129(5):1011-1019

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN