Laser-evoked brain potentials (LEPs)

In 1975, Mor and Carmon introduced infrared laser stimulators as tools to explore nociception in humans. Allowing brief, synchronous, and selective activation of cutaneous Adelta- and C-fibre nociceptors, laser heat stimulators are now used extensively to study nociception in humans.

Heid C, Mouraux A, Treede RD, Schuh-Hofer S, Rupp A, Baumgärtner U. J Neurophysiol (2020); in press.

Van Assche DCF, Plaghki L, Masquelier E, Hatem SM. Eur J Pain (2020); 24(2):448-456. [PDF]

Mancini F, Pepe A, Di Stefano G, Mouraux A, Iannetti GD. eNeuro (2018); 5(5): ENEURO.0014-18.2018. [PDF]

Liberati G, Algoet M, Klöcker A, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A. Nature: Scientific Reports (2018); 8(1): 8265. [PDF]

Mouraux A. In : Pain persistence after surgery and altered central processing: science and clinical practice. Wilder-Smith OHG, Arendt-Nielsen L, Yarnitski D and Vissers K (Eds). IASP Press, (2015).

Caty G, Hu L, Legrain V, Plaghki L, Mouraux A. Pain (2013); 154(11):2521-8. [PDF]

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Researchers involved :

  •  Léon Plaghki

  • André Mouraux

  • Valery Legrain

  • Cédric Lenoir

  • Emanuel van den Broeke

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)