Emanuel van den Broeke - postdoc (FRC)

The main objective of my research is to study pain - or nociception- induced central nervous system plasticity. Currently, my studies are focused on characterizing changes in nociceptive pathways that lead or contribute to hyperalgesia, and I am, thereby, particularly interested in the phenomenon of "central sensitization"; the increase responsiveness of nociceptive neurons in the central nervous system that generates widespread hyperalgesia ("secondary hyperalgesia").

Publications

Royal Society Open Science

van den Broeke EN, Vanmaele T, Mouraux A, Stouffs A, Biurrun-Manresa J, Torta DM

in press.

Perceptual correlates of homosynaptic long term potentiation in human nociceptive pathways: a replication study

2020

Nature: Scientific Reports

Liberati G, Mulders D, Algoet M, van den Broeke EN, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.

10: 22319

Insular responses to transient painful and non-painful thermal and mechanical spinothalamic stimuli recorded using intracerebral EEG

2020

Clinical Neurophysiology

van den Broeke EN, de Hemptinne P, Mercken M, Torta DM, Lambert J, Mouraux A.

131(10):2491-2498.

Central sensitization of nociceptive pathways demonstrated by robot-controlled pinprick-evoked brain potentials

2020

European Journal of Pain

Cayrol T, Lebleu J, Mouraux A, Roussel N, Pitance L, van den Broeke E.

24(8):1585-1597.

Within- and between-session reliability of secondary hyperalgesia induced by electrical high-frequency stimulation

2020

Pain

Torta DME, De Laurentis M, Eichin KN, Von Leupoldt A, van den Broeke EN, Vlaeyen J.

161(7):1459-1469.

A highly cognitive demanding working memory task may prevent the development of nociceptive hypersensitivity

2020

Journal of Neurophysiology

Gousset S, Mouraux A, van den Broeke EN.

123(1):323-328

Burst-like conditioning electrical stimulation is more efficacious than continuous stimulation for inducing secondary hyperalgesia in humans

2020

Cortex

Filbrich L, van den Broeke E, Legrain V, Mouraux .

124:193-203

The focus of spatial attention during the induction of central sensitization can modulate the subsequent development of secondary hyperalgesia

2020

Journal of Neurophysiology

van den Broeke EN, Gousset S, Bouvy J, Stouffs A, Lebrun L, van Neerven SGA, Mouraux A.

122(3):994-1001

Heterosynaptic facilitation of mechanical nociceptive input is dependent on the frequency of conditioning stimulation

2019

Journal of Psychosomatic Research

van den Broeke EN, Van den Bergh O.

119:51-52

Central sensitization in humans: Popular phrase or useful concept?

2019

Journal of Neurophysiology

van den Broeke EN, Hartgerink DM, Butler J, Lambert J, Mouraux A.

121(5):1621-1632

Central sensitization increases the pupil dilation elicited by mechanical pinprick stimulation

2019

Pain Reports

Cayrol T, Pitance L, Roussel N, Mouraux A, van den Broeke EN.

3(6): e691

No evidence of widespread mechanical pressure hyperalgesia after experimentally-induced central sensitization via skin nociceptors

2018

F1000 Research

van den Broeke EN.

Central sensitization and pain hypersensitivity: some critical considerations

2018

PLoS One

Manresa JB, Andersen OK, Mouraux A, van den Broeke EN.

13(9):e0203365

High frequency electrical stimulation induces a long-lasting enhancement of event-related potentials but does not change the perception elicited by intra-epidermal electrical stimuli delivered to the area of increased mechanical pinprick sensitivity

2018

Journal of Physiology

Lenoir C, Plaghki L, Mouraux A, van den Broeke EN.

596(18):4443-4455.

Quickly-responding C-fiber nociceptors contribute to heat hypersensitivity in the area of secondary hyperalgesia

2018

Clinical Psychological Science

van den Broeke EN, Torta DM, Van den Bergh O.

in press

Central sensitization: explanation or phenomenon?

2018

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN