Maxime Algoet - PhD student

The general objective of my PhD project was to develop novel noninvasive means to characterize activity-dependent changes in brain function related to central sensitization and chronic pain. At the core of my project was the development of a novel approach based on the recording of TMS-evoked BOLD responses sampled using concurrent TMS-fMRI. As a first step, this was used to characterize changes in cortical excitability and functional connectivity within different brain areas induced by a sustained experimental pain. Subsequently, this approach could be used to study changes in brain function related to chronic pain. In parallel, I was also interested in studying the changes in motor excitability induced by an experimental pain. I combined TMS of the primary motor cortex with, respectively, brief and sustained nociceptive stimulation to characterize the spinal and supraspinal pain-motor interactions triggered by noxious stimulation



Publications
Nature: Scientific Reports
Liberati G, Mulders D, Algoet M, van den Broeke EN, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.
10: 22319
Insular responses to transient painful and non-painful thermal and mechanical spinothalamic stimuli recorded using intracerebral EEG
2020
Neuroimage
Liberati G, Algoet M, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.
188:70-83
Tonic thermonociceptive stimulation selectively modulates ongoing neural oscillations in the human posterior insula: evidence from intracerebral EEG
2018
Journal of Physiology
Lenoir C*, Algoet M*, Mouraux A.
596(19):4767-4787
Deep continuous theta burst stimulation of the operculo-insular cortex selectively affects Adelta-fiber heat pain
2018
Neuroscience
Algoet M, Duqué J, Iannetti GD, Mouraux A.
386: 240-255
Temporal profile and limb-specificity of phasic pain-evoked changes in motor excitability
2018
Nature: Scientific Reports
Liberati G, Algoet M, Klöcker A, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.
8(1): 8265
Habituation of phase-locked local field potentials and gamma-band oscillations recorded from the human insula
2018
Brain Stimulationation
Lenoir C*, Algoet M*, Vanderclausen C, Peeters A, Ferrao Santos S, Mouraux A.
11(5):1187-1188
Report of one confirmed generalized seizure and one suspected partial seizure induced by deep continuous theta burst stimulation of the right operculo-insular cortex
2018
Cerebral Cortex
Liberati G, Klöcker A, Algoet M, Mulders D, Safronova MM, Ferrao Santos S, Vaz JG, Raftopoulos C, Mouraux A.
28(10):3650-3664.
Gamma-band oscillations preferential for nociception can be recorded in the human insula
2017
PLoS ONE
Torta D, Legrain V, Algoet M, Olivier E, Duqué J, Mouraux A.
20; 8(8): e73263
Theta burst stimulation applied over primary motor and somatosensory cortices produces analgesia unrelated to the changes in nociceptive event-related potentials
2013