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André Mouraux - Principal investigator (IONS/COSY)

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Using non-invasive functional neuroimaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), combined with novel techniques to selectively activate specific classes of nociceptive afferents, the research performed by the team of André Mouraux (IONS/COSY) follows two main axes. First, to understand how the human brain processes nociceptive sensory input and how this leads to the perception of pain. Second, to understand the plastic changes in nociceptive pathways that occur after inflammation, injury or sustained nociceptive input that induce peripheral and central sensitization and may underlie the development of chronic pain in humans.

Publications

2024

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Effect of limb position change on capsaicin-evoked pain: evidence of interplays between the vascular and nociceptive systems?

Eur J Pain

Courtin AS, Knaepen, C, Mouraux A, van Neerven SGA

in press.

2024

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Studying the effect of expectations on high-frequency electrical stimulation-induced pain and pinprick hypersensitivity

J Pain

Gousset S, Cayrol T, Papleux M, Meulders A, Mouraux A, van den Broeke EN

in press

2024

Systematic review and co-ordinate based meta-analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensitization

Eur J Pain

Clarke S, Rogers R, Wanigasekera V, Fardo F, Pia H, Nochi Z, Macian N, Leray V, Finnerup NB, Pickering G, Mouraux A, Truini A, Treede RD, Garcia-Larrea L, Tracey I.

in press.

2023

Modulation of the spinal N13 SEP component by high- and low-frequency electrical stimulation. Experimental pain models matter

Clinical Neurophysiology

Leone C, Di Pietro G, Salman Y, Galosi E, Di Stefano G, Caspani O, Garcia-Larrea L, Mouraux A, Treede RD, Truini A

156:28-37.

2023

Why Europe needs a pain research strategy

Eur J Pain

Pickering G, O'Keeffe M, Bannister K, Becker S, Cottom S, Cox FJ, Eisenberg E, Finn DP, Graven-Nielsen T, Meeus M, Mouraux A, Tölle T, Garcia-Larrea L, Fullen BM.

in press.

2023

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Intra-operative electroencephalogram frontal alpha-band spectral analysis and postoperative delirium in cardiac surgery: A prospective cohort study

Eur J Anaesthesiol

Khalifa C, Lenoir C, Robert A, Watremez C, Kahn D, Mastrobuoni S, Aphram G, Ivanoiu A, Bonhomme V, Mouraux A, Momeni M.

40(10):777-787.

2023

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Pinprick-induced gamma-band oscillations are not a useful electrophysiological marker of pinprick hypersensitivity in humans

Clin Neurophysiol

Gousset S, Torta DM, Mouraux A, Lambert J, van den Broeke EN.

53:102-110.

2023

Poor pre-operative performance at Clock Drawing Test is associated with postoperative decline in olfaction in older patients: an observational pilot study

BMC Anesthesiology

Van Regemorter V, Coulie R, Dollase J, Momeni M, Stouffs A, Quenon L, Mouraux A, Huart C

23:295

2023

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Influence of skin type and laser wavelength on laser evoked potentials

Eur J Pain

Frahm KS, Gervasio S, Arguissain F, Mouraux A

in press.

2023

Perceptual simultaneity between nociceptive and visual stimuli depends on their spatial congruence

Exp Brain Res

Manfron L, Filbrich L, Molitor V, Farnè A, Mouraux A, Legrain V

in press

2023

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Comparison between pupillometry and numeric pain rating scale for pain assessments in communicating adult patients in the emergency department

Eur J Pain

Gregoire C, Charier D, de Bergeyck R, Mouraux A, Van Ouytsel F, Lambert R, Zhou N, Lavand'homme P, Penaloza A, Pickering G.

in press.

2023

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Pain-free default mode network connectivity contributes to tonic experimental pain intensity beyond the role of negative mood and other pain-related factors

Eur J Pain

Alhajri N, Boudreau SA, Mouraux A, Graven-Nielsen T.

in press.

2023

The test-retest reliability of large and small fiber nerve excitability testing with threshold tracking

Clinical Neurophysiology Practice

Pia H, Nochi Z, Kristensen AG, Pelz B, Goetz M, Hoeink JN, Blockeel AJ, Mouraux A, Truini A, Finnerup NB, Phillips KG, Treede RD, Tankisi H

8: 71-78.

2023

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Neural evidence for functional roles of tactile and visual feedback in the application of myoelectric prosthesis

J Neural Eng

Su S, Chai G, Xu W, Meng J, Sheng X, Mouraux A, Zhu X.

20(1).

2023

Spatial summation of cold and warm detection: evidence for increased precision when brisk stimuli are delivered over larger area

Neuroscience Letters

Courtin AS, Delvaux A, Dufour A, Mouraux A

in press.

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