Alexandre Stouffs - PhD student (IMI2 PAINCARE)
My PhD is conducted in the framework of a large-scale Innovative Medicines Initiative (IMI PAIN-CARE) project, subtopic BioPain. The aim of this subtopic is to identify and validate a number of functional biomarkers based on non-invasive measures of neural activity (peripheral measures of nerve excitability, spinal and brainstem reflexes, measures of brain activity using electroencephalography [EEG] and functional magnetic resonance imaging [MRI] that can be used in humans to assess the effects of a given drug on the nociceptive system. If successful, these biomarkers would be used in future studies for the early stages of the pharmacological development of novel treatments for pain, and back-translated to animal models.
Publications
Perceptual correlates of homosynaptic long term potentiation in human nociceptive pathways: a replication study
Royal Society Open Science
van den Broeke EN, Vanmaele T, Mouraux A, Stouffs A, Biurrun-Manresa J, Torta DM
Heterosynaptic facilitation of mechanical nociceptive input is dependent on the frequency of conditioning stimulation
Journal of Neurophysiology
van den Broeke EN, Gousset S, Bouvy J, Stouffs A, Lebrun L, van Neerven SGA, Mouraux A.
IMI-PAINCARE, BIOPAIN : validation chez lhomme de nouveaux biomarqueurs fonctionnels pour le dÈveloppement pharmacologique de traitements de la douleur
Stouffs A, Lebrun L, Mouraux A.
Philips Intellivue NMT module: variability of initial measurements
Journal of Clinical Monitoring and Computing
Stouffs A, Ibsen A, Jamart J, Dubois V, Dubois PE.
Intraoperatively diagnosed tracheal tear during a parathyroidectomy with previously undiagnosed tracheomalacia: a case report
Acta Anaesthesiologica Belgica
