Adriana Salatino - postdoc (ARC GABA-AD)

Group : 

André Mouraux

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Studies have suggested that Alzheimer's disease (AD) is related to changes in brain function that are present already at very early, pre-clinical stages of the disease. For example, recent functional neuroimaging studies have shown early alterations in brain connectivity, and that these alterations are most prominent in highly-connected cortical "hub areas". These hub areas are also those that are most affected by AD lesions. These findings support the view that AD pathology could, at least in part, result from an activity-dependent degeneration. Initial excessive neural firing in hub areas due to increased excitability or connectivity could lead to later neurodegeneration and disruption of connectivity. Very recently, studies conducted by Prof. JN Octave (UCL) have suggested that AD could be related to a decrease in the expression of the cellular Cl- ion extruder KCC2, leading to an increase in intracellular Cl- and, thereby, an inhibitory-to-excitatory shift of GABAA receptor activity. The aim of the present study is to test whether GABAergic neurotransmission is altered at early pre-clinical and pre-demential stages of AD as compared to matched healthy controls.

Publications

2021

Zero gravity induced by parabolic flight enhances automatic capture and weakens voluntary maintenance of visuospatial attention.

NPJ Microgravity

Salatino A, Iacono C, Gammeri R, Chiadò ST, Lambert J, Sulcova D, Mouraux A, George MS, Roberts DR, Berti A, Ricci R.

in press.

2021

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Improvement of Impulsivity and Decision Making by Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex in a Patient with Gambling Disorder.

J Gambl Stud

Ninghetto M, Belli F, Nobili M, Mouraux A, Ricci R.

in press.

2019

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Everything is (still) illuminated: Dual right cathodal-left anodal tDCS of PPC prevents fatigue on a visual detection task

Brain Stimulation

Sarasso P, Ninghetto M, Salatino A, Ronga I, Bongiardina A, Iarrobino I, Neppi-Modona M, Ricci R.

in press.

2018

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As long as that is my hand, that willed action is mine: Timing of agency triggered by body ownership

Consciousness and Cognition

Burin D, Pyasik M, Ronga I, Cavallo M, Salatino A, Pia L.

in press.

2018

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Anodal Transcranial Direct Current Stimulation of the motor cortex reduces chronic pain in Alcock canal syndrome

Brain Stimulation

Ricci R, Ghiggia A, La Rosa I, Milano A, Troni W, George MS, Borckardt JJ, Castelli L, Salatino A.

in press.

2018

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Biased Visuospatial Attention in Cervical Dystonia

Journal of the International Neuropsychological Society

Chillemi G, Formica C, Salatino A, Calamuneri A, Girlanda P, Morgante F, Milardi D, Terranova C, Cacciola A, Quartarone A, Ricci R.

in press.

2017

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Comparing intensities and modalities within the sensory attenuation paradigm: Preliminary evidence

Journal of Advanced Research

Burin D, Battaglini A, Pia L, Falvo G, Palombella M, Salatino A.

in press.

2017

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That is my hand! Therefore, that is my willed action: How body ownership acts upon conscious awareness of willed actions

Cognition

Burin D, Pyasik M, Salatino A, Pia L.

in press.

2017

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Investigating the link between drug-naive first episode psychoses (FEPs), weight gain abnormalities and brain structural damages: Relevance and implications for therapy

Progress in Neuro-Psychopharmacology & Biological Psychiatry

Minichino A, Ando A, Francesconi M, Salatino A, Delle Chiaie R, Cadenhead K.

in press.

2016

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Sexual Well-Being in Patients with Blepharospasm, Spasmodic Torticollis, and Hemifacial Spasm: A Pilot Study

Frontiers in Psychology

Perozzo P, Salatino A, Cerrato P, Ricci R.

in press.

2016

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Cognitive and Neurophysiological Effects of Non-invasive Brain Stimulation in Stroke Patients after Motor Rehabilitation

Frontiers in Behavioral Neuroscience

DAgata F, Peila E, Cicerale A, Caglio MM, Caroppo P, Vighetti S, Piedimonte A, Minuto A, Campagnoli M, Salatino A, Molo MT, Mortara P, Pinessi L, Massazza G.

in press.

2016

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Rorschach Performance Assessment System (R-PAS) and vulnerability to stress: A preliminary study on electrodermal activity during stress

Psychiatry Research

Giromini L, Ando A, Morese R, Salatino A, Di Girolamo M, Viglione DJ, Zennaro A.

in press.

2016

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Effects of attentional and cognitive variables on unilateral spatial neglect

Neuropsychologia

Ricci R, Salatino A, Garbarini F, Ronga I, Genero R, Berti A, Neppi-Mòdona M.

in press.

2015

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Embodied simulation and ambiguous stimuli: The role of the mirror neuron system

Brain Research

Ando A, Salatino A, Giromini L, Ricci R, Pignolo C, Cristofanelli S, Ferro L, Viglione DJ, Zennaro A.

in press.

2015

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Dual task-related gait changes in patients with mild cognitive impairment

Functional Neurology

Nascimbeni A, Caruso S, Salatino A, Carenza M, Rigano M, Raviolo A, Ricci R.

in press.