Maxime Algoet - PhD student
The general objective of my PhD project is to develop novel noninvasive means to characterize activity-dependent changes in brain function related to central sensitization and chronic pain. At the core of my project is the development of a novel approach based on the recording of TMS-evoked BOLD responses sampled using concurrent TMS-fMRI. As a first step, this will be used to characterize changes in cortical excitability and functional connectivity within different brain areas induced by a sustained experimental pain. Subsequently, this approach could be used to study changes in brain function related to chronic pain. In parallel, I am also interested in studying the changes in motor excitability induced by an experimental pain. I combined TMS of the primary motor cortex with, respectively, brief and sustained nociceptive stimulation to characterize the spinal and supraspinal pain-motor interactions triggered by noxious stimulation
Publications
Tonic thermonociceptive stimulation selectively modulates ongoing neural oscillations in the human posterior insula: evidence from intracerebral EEG
Liberati G, Algoet M, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.
Deep continuous theta burst stimulation of the operculo-insular cortex selectively affects Adelta-fiber heat pain
Lenoir C*, Algoet M*, Mouraux A.
Temporal profile and limb-specificity of phasic pain-evoked changes in motor excitability
Algoet M, Duqué J, Iannetti GD, Mouraux A.
Habituation of phase-locked local field potentials and gamma-band oscillations recorded from the human insula
Nature: Scientific Reports
Liberati G, Algoet M, Klöcker A, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.
Report of one confirmed generalized seizure and one suspected partial seizure induced by deep continuous theta burst stimulation of the right operculo-insular cortex
Lenoir C*, Algoet M*, Vanderclausen C, Peeters A, Ferrao Santos S, Mouraux A.
Gamma-band oscillations preferential for nociception can be recorded in the human insula
Liberati G, Klöcker A, Algoet M, Mulders D, Safronova MM, Ferrao Santos S, Vaz JG, Raftopoulos C, Mouraux A.
Theta burst stimulation applied over primary motor and somatosensory cortices produces analgesia unrelated to the changes in nociceptive event-related potentials
Torta D, Legrain V, Algoet M, Olivier E, Duqué J, Mouraux A.
