Sabien van Neerven - former postdoc (UCL MoveIn)

Group : 

André Mouraux

The general objective of my project was to characterize the effects of topical capsaicin treatment on the changes in function and structure of nociceptive pathways associated with the development of chronic neuropathic pain and/or central sensitization. The project was translational, from bench to bedside, combining work performed in an animal model of neuropathic pain and work performed in patients suffering from chronic post-operative pain.

Publications

2020

Capsaicin-induced skin desensitization differentially affects A-delta and C-fiber mediated heat sensitivity

Frontiers in Pharmacology

van Neerven SGA, Mouraux A.

in press.

2019

Heterosynaptic facilitation of mechanical nociceptive input is dependent on the frequency of conditioning stimulation

Journal of Neurophysiology

van den Broeke EN, Gousset S, Bouvy J, Stouffs A, Lebrun L, van Neerven SGA, Mouraux A.

in press.

2018

Cell-enrichment with olfactory ensheathing cells has limited local extra beneficial effects on nerve regeneration supported by the nerve guide Perimaix

Journal of Tissue Engineering and Regenerative Medicine

Boecker AH, Bozkurt A, Kim BS, Altinova H, Tank J, Deumens R, Tolba R, Weis J, Brook GA, Pallua N, van Neerven S.

in press.

2017

Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain

Journal of Neuroinflammation

Doyen PJ, Vergouts M, Pochet A, Desmet N, van Neerven S, Brook G, Hermans E.

in press.

2017

Clinical and biometrical 12 months follow up study in patients after reconstruction of the sural nerve biopsy defect by the collagen-based nerve guide Neuromaix

European Journal of Medical Research

Bozkurt A, Claeys KG, Schrading S, Rose JV, Sellhaus B, Schulz JB, Weis J, Pallua N and van Neerven S.

in press.

2016

Functional recovery not correlated with axon regeneration through OEC-seeded scaffolds in a model of acute SCI

Journal of Tissue Engineering and Regenerative Medicine

Altinova H, Möllers S, Deumens R, Gerardo-Nava J, Führmann T, van Neerven S, Bozkurt A, Heschel I, Weis J, and Brook GA.

in press.

2016

Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model

European Journal of Neuroscience

Boecker AH, van Neerven S, Scheffel J, Tank J, Altinova H, Seidensticker K, Deumens R, Tolba R, Weis J, Brook GA, Pallua N and Bozkurt A.

in press.

2016

Efficient bridging of 20 mm rat sciatic nerve lesions with a longitudinally micro-structured collagen scaffold

Biomaterials

Bozkurt A, Boecker A, Tank J, Altinova H, Deumens R, Dabhi C, Tolba R, Weis J, Brook GA, Pallua N, van Neerven SG.

in press.

2016

Two-component collagen nerve guides support axonal regeneration in the rat peripheral nerve injury model

Journal of Tissue Engineering and Regenerative Medicine

van Neerven SG, Haastert-Talini K, Boecker A, Schriever T, Dabhi C, Claeys K, Deumens R, Brook GA, Weis J, Pallua N, Bozkurt A.

in press.

2016

Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model

European Journal of Neuroscience

Boecker AH, van Neerven SG, Scheffel J, Tank J, Altinova H, Seidensticker K, Deumens R, Tolba R, Weis J, Brook GA, Pallua N, Bozkurt A.

in press.

2014

Human Schwann cells seeded on a novel collagen-based microstructured nerve guide survive, proliferate, and modify neurite outgrowth

BioMed Research International

van Neerven SG, Krings L, Haastert-Talini K, Vogt M, Tolba RH, Brook G, Pallua N, Bozkurt A.

in press.

2014

The proximal medial sural nerve biopsy model: a standardised and reproducible baseline clinical model for the translational evaluation of bioengineered nerve guides

BioMed Research International

Bozkurt A, van Neerven SG, Claeys KG, ODey DM, Sudhoff A, Brook GA, Sellhaus B, Schulz JB, Weis J, Pallua N.

in press.

2014

Differences in degradation behavior of two non-cross-linked collagen barrier membranes: an in vitro and in vivo study

Clinical Oral Implantations Research

Bozkurt A, Apel C, Sellhaus B, van Neerven S, Wessing B, Hilgers RD, Pallua N.

in press.

2013

Schwann cell migration and neurite outgrowth are influenced by media conditioned by epineurial fibroblasts

Neuroscience

van Neerven SG, Pannaye P, Bozkurt A, Van Nieuwenhoven F, Joosten E, Hermans E, Taccola G, Deumens R.

in press.

2012

Retrograde tracing and toe spreading after experimental autologous nerve transplantation and crush injury of the sciatic nerve: a descriptive methodological study

Journal of Brachial Plexus and Peripheral Nerve Injury

van Neerven SG, Bozkurt A, ODey DM, Scheffel J, Boecker AH, Stromps JP, Dunda S, Brook GA, Pallua N.

in press.

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN