Electroencephalography (EEG)

Scalp electroencephalography (EEG) can be used to record ongoing oscillatory brain activity, stimulus-evoked brain potentials (event-related brain potentials, ERP). The recorded signals correspond to variations in scalp potentials, hypothesized to predominantly result from sudden and synchronized changes in postsynaptic activity, occurring in the apical dendrites of pyramidal neurons. Another approach is EEG "frequency tagging", in which a sensory stimulus is periodically repeated at a constant frequency, thereby eliciting a periodic change in the EEG signal which can be identified in the frequency domain.


Event-related potentials (ERPs)

To extract evoked potentials from the ongoing, non event-related, electrical brain activity, the event is usually repeated such as to allow the averaging of successive peristimulus EEG recordings. The principle underlying time-domain averaging techniques is that averaging successive EEG epochs should cancel out the contribution of signals which are not ‘time-locked’ or ‘stationary’ to the onset of the event while it should preserve evoked activity which is assumed to occur with a constant time-delay. The fraction of the signal which is cancelled-out by the averaging procedure is often referred to as ‘additive noise’.

Event-related potentials typically consist of a series of voltage polarity changes, observed as peaks and troughs in the average waveform. These potentials can be classified according to their relative timing to stimulus onset, their polarity, and their magnitude. In most cases, each individualized ERP deflection corresponds to neural activity arising from several temporally overlapping sources. As ERPs provide a high temporal resolution, they can be used to characterize the chronometry of the different neural processes involved in perception. Indeed, depending on their modality, sensory stimuli elicit a series of sensory or exogenous ERP peaks which reflect the initial processing occurring in modality-specific cortical areas. Following these peaks, later components may be recorded, which are thought to reflect more integrative and endogenous aspects of perception.


More about EEG signal processing :

Researchers involved

Publications

Frontiers in Human Neuroscience

Rating the Intensity of a Laser Stimulus, but Not Attending to Changes in Its Location or Intensity Modulates the Laser-Evoked Cortical Activity

2020

Torta DME, Ninghetto M, Ricci R, Legrain V.

14:120

Clinical Neurophysiology

Improving the recording of pinprick-evoked brain potentials in the context of central sensitization: the use of robot-controlled mechanical pinprick stimulation and a stimulus evaluation task

2020

van den Broeke EN, de Hemptinne P, Mercken M, Torta DM, Lambert J, Mouraux A.

in press

Journal of Neurophysiology

Early gamma-oscillations as correlate of localized nociceptive processing in primary sensorimotor cortex

2020

Heid C, Mouraux A, Treede RD, Schuh-Hofer S, Rupp A, Baumgärtner U.

123(5):1711-1726

Journal of Neurophysiology

Central sensitization increases the pupil dilation elicited by mechanical pinprick stimulation

2019

van den Broeke EN, Hartgerink DM, Butler J, Lambert J, Mouraux A.

121(5):1621-1632

Brain

The search for pain biomarkers in the human brain

2018

Mouraux A, Iannetti GD.

141(12):3290-3307

Journal of Neuroscience

Visuomotor correlates of conflict expectation in the context of motor decisions

2018

Derosiere G, Klein PA, Nozaradan S, Zénon A, Mouraux A, Duqué J.

38(44):9486-9504

PLoS One

High frequency electrical stimulation induces a long-lasting enhancement of event-related potentials but does not change the perception elicited by intra-epidermal electrical stimuli delivered to the area of increased mechanical pinprick sensitivity

2018

Manresa JB, Andersen OK, Mouraux A, van den Broeke EN.

13(9):e0203365

eNeuro

Characterising the short-term habituation of event-related evoked potentials

2018

Mancini F, Pepe A, Di Stefano G, Mouraux A, Iannetti GD.

5(5): ENEURO.0014-18.2018

ICONIP

Linear Periodic Discriminant Analysis

2018

Mulders D, de Boot C, Lejeune N, Mouraux A, Verleysen M.

accepted

Journal of Neuroscience Methods

EEG time-warping to study non-strictly-periodic EEG signals related to the production of rhythmic movements

2018

Chemin B, Huang G, Mulders D, Mouraux A.

308:106-115

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN