Infrared laser stimulation
In 1975, Mor and Carmon introduced infrared laser stimulators as tools to explore nociception in humans. Allowing brief, synchronous, and selective activation of cutaneous Adelta- and C-fibre nociceptors, laser heat stimulators are now used extensively to study nociception in humans. Recently, we have collaborated to the development of a novel CO2 laser stimulator whose power is regulated using a feedback control based on an online measurement of skin temperature at the site of stimulation (Laser Stimulation Device, SIFEC, Belgium).

Researchers involved
Publications
Nature: Scientific Reports
Insular responses to transient painful and non-painful thermal and mechanical spinothalamic stimuli recorded using intracerebral EEG
2020
Liberati G, Mulders D, Algoet M, van den Broeke EN, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.
10: 22319
Neuroscience
New insights into cutaneous laser stimulation – dependency on skin and laser type
2020
Frahm KS, Gervasio S, Arguissain F, Mouraux A.
448:71-84.
Frontiers in Human Neuroscience
Rating the Intensity of a Laser Stimulus, but Not Attending to Changes in Its Location or Intensity Modulates the Laser-Evoked Cortical Activity
2020
Torta DME, Ninghetto M, Ricci R, Legrain V.
14:120
Journal of Clinical Medicine
Does motor cortex engagement during movement preparation differentially inhibit nociceptive processing in patients with chronic whiplash associated disorders, chronic fatigue syndrome and healthy controls? An experimental study
2020
Goudman L, Mouraux A, Daenen L, Nijs J, Cras P, Roussel N, Moens M, Lenoir D, Coppieters I, Huysmans E, De Kooning M.
9(5): E1520
Pain Medicine
Processing of laser-evoked potentials in patients with chronic whiplash-associated disorders, chronic fatigue syndrome, and healthy controls: a case-control study
2020
Goudman L, Daenen L, Mouraux A, Nijs J, Cras P, Roussel N, Moens M, Coppieters I, Huysmans E, De Kooning M.
21(10):2553-2563.
PLoS ONE
Dynamics of the perception and EEG signals triggered by tonic warm and cool stimulation
2020
Mulders D, de Bodt C, Lejeune N, Dufour A, Verleysen M, Mouraux A.
15(4):e0231698
Journal of Neurophysiology
Early gamma-oscillations as correlate of localized nociceptive processing in primary sensorimotor cortex
2020
Heid C, Mouraux A, Treede RD, Schuh-Hofer S, Rupp A, Baumgärtner U.
123(5):1711-1726
Frontiers in Human Neuroscience
Rating the intensity of a laser stimulus, but not attending to changes in its location or intensity modulates the laser-evoked cortical activity
2020
Torta DME, Ninghetto M, Ricci R, Legrain V.
0.666666667
European Journal of Pain
Fibromyalgia syndrome - A laser-evoked potentials study unsupportive of small nerve fibre involvement
2020
Van Assche DCF, Plaghki L, Masquelier E, Hatem SM.
24(2):448-456
eNeuro
Characterising the short-term habituation of event-related evoked potentials
2018
Mancini F, Pepe A, Di Stefano G, Mouraux A, Iannetti GD.
5(5): ENEURO.0014-18.2018