EEG frequency tagging

Studies have shown that the periodic repetition or modulation of a stimulus can induce a sustained periodic EEG response at the frequency of stimulation and its harmonics, often referred to as steady-state evoked potential (SS-EP). Unlike event-related potentials (ERPs), which reflect phasic cortical activity triggered by a transient stimulus. SS-EPs reflect sustained cortical activity induced by the entrainment of neuronal populations responding to the stimulus. Our objective is to exploit this "EEG frequency-tagging" technique to explore the cortical activity underlying the perception of sustained pain in humans. This is achieved, for example, using a temperature-controlled CO2 laser stimulator to periodically activate heat-sensitive nociceptors of the skin. Using this technique, we showed that it is possible to isolate cortical activity specifically related to the activation of heat-sensitive C-fiber nociceptors.

Researchers involved

Publications

2020

Dynamics of the perception and EEG signals triggered by tonic warm and cool stimulation

PLoS ONE

Mulders D, de Bodt C, Lejeune N, Courtin A, Liberati G, Verleysen M, Mouraux A.

15(4):e0231698

2018

Spatial Filtering of EEG Signals to Identify Periodic Brain Activity Patterns

Latent Variable Analysis and Signal Separation LVA/ICA

Mulders D, de Bodt C, Lejeune N, Mouraux A, Verleysen M.

In: Deville Y, Gannot S, Mason R, Plumbley M, Ward D (eds). Lecture notes in Computer Science, vol 10891. Springer

2016

EEG frequency tagging using ultra-slow periodic heat stimulation of the skin reveals cortical activity specifically related to C fiber thermonociceptors

Neuroimage

Colon E, Liberati G, Mouraux A.

146:266-274

2016

Absence of Evidence or Evidence of Absence? Commentary: Captured by the pain: Pain steady-state evoked potentials are not modulated by selective spatial attention

Frontiers in Human Neuroscience

Colon E, Mouraux A.

0.175

2015

Frequency-tagging of steady-state evoked potentials to explore the crossmodal links in spatial attention between vision and touch

Psychophysiology

Colon E, Huang G, Legrain V, Mouraux A.

2014

EEG frequency-tagging to dissociate the cortical responses to nociceptive and non-nociceptive stimuli

Journal of Cognitive Neuroscience

Colon E, Legrain V, Mouraux A.

26(10):2262-74

2012

Steady-state evoked potentials to study the processing of tactile and nociceptive somatosensory input in the human brain

Neurophysiologie Clinique - Clinical Neurophysiology

Colon E, Legrain V, Mouraux A.

42(5):315-23

2011

Steady-state evoked potentials to tag specific components of nociceptive cortical processing

Neuroimage

Colon E, Nozaradan S, Legrain V, Mouraux A.

60(1):571-581

2011

Nociceptive steady-state evoked potentials elicited by rapid periodic thermal stimulation of cutaneous nociceptors

Journal of Neuroscience

Mouraux A, Iannetti GD, Colon E, Legrain V, Nozaradan S, Plaghki L.

31(16): 6079-87

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN