EEG frequency tagging
Studies have shown that the periodic repetition or modulation of a stimulus can induce a sustained periodic EEG response at the frequency of stimulation and its harmonics, often referred to as steady-state evoked potential (SS-EP). Unlike event-related potentials (ERPs), which reflect phasic cortical activity triggered by a transient stimulus. SS-EPs reflect sustained cortical activity induced by the entrainment of neuronal populations responding to the stimulus. Our objective is to exploit this "EEG frequency-tagging" technique to explore the cortical activity underlying the perception of sustained pain in humans. This is achieved, for example, using a temperature-controlled CO2 laser stimulator to periodically activate heat-sensitive nociceptors of the skin. Using this technique, we showed that it is possible to isolate cortical activity specifically related to the activation of heat-sensitive C-fiber nociceptors.
Spatial Filtering of EEG Signals to Identify Periodic Brain Activity Patterns
Latent Variable Analysis and Signal Separation LVA/ICA
Mulders D, de Bodt C, Lejeune N, Mouraux A, Verleysen M.
In: Deville Y, Gannot S, Mason R, Plumbley M, Ward D (eds). Lecture notes in Computer Science, vol 10891. Springer
EEG frequency tagging using ultra-slow periodic heat stimulation of the skin reveals cortical activity specifically related to C fiber thermonociceptors
Colon E, Liberati G, Mouraux A.
Absence of Evidence or Evidence of Absence? Commentary: Captured by the pain: Pain steady-state evoked potentials are not modulated by selective spatial attention
Frontiers in Human Neuroscience
Colon E, Mouraux A.
Steady-state evoked potentials to study the processing of tactile and nociceptive somatosensory input in the human brain
Neurophysiologie Clinique - Clinical Neurophysiology
Colon E, Legrain V, Mouraux A.
Nociceptive steady-state evoked potentials elicited by rapid periodic thermal stimulation of cutaneous nociceptors
Journal of Neuroscience
Mouraux A, Iannetti GD, Colon E, Legrain V, Nozaradan S, Plaghki L.