EEG frequency tagging

Studies have shown that the periodic repetition or modulation of a stimulus can induce a sustained periodic EEG response at the frequency of stimulation and its harmonics, often referred to as steady-state evoked potential (SS-EP). Unlike event-related potentials (ERPs), which reflect phasic cortical activity triggered by a transient stimulus. SS-EPs reflect sustained cortical activity induced by the entrainment of neuronal populations responding to the stimulus. Our objective is to exploit this "EEG frequency-tagging" technique to explore the cortical activity underlying the perception of sustained pain in humans. This is achieved, for example, using a temperature-controlled CO2 laser stimulator to periodically activate heat-sensitive nociceptors of the skin. Using this technique, we showed that it is possible to isolate cortical activity specifically related to the activation of heat-sensitive C-fiber nociceptors.

Researchers involved

Publications

PLoS ONE

Dynamics of the perception and EEG signals triggered by tonic warm and cool stimulation

2020

Mulders D, de Bodt C, Lejeune N, Courtin A, Liberati G, Verleysen M, Mouraux A.

15(4):e0231698

Latent Variable Analysis and Signal Separation LVA/ICA

Spatial Filtering of EEG Signals to Identify Periodic Brain Activity Patterns

2018

Mulders D, de Bodt C, Lejeune N, Mouraux A, Verleysen M.

In: Deville Y, Gannot S, Mason R, Plumbley M, Ward D (eds). Lecture notes in Computer Science, vol 10891. Springer

Neuroimage

EEG frequency tagging using ultra-slow periodic heat stimulation of the skin reveals cortical activity specifically related to C fiber thermonociceptors

2016

Colon E, Liberati G, Mouraux A.

146:266-274

Frontiers in Human Neuroscience

Absence of Evidence or Evidence of Absence? Commentary: Captured by the pain: Pain steady-state evoked potentials are not modulated by selective spatial attention

2016

Colon E, Mouraux A.

0.175

Psychophysiology

Frequency-tagging of steady-state evoked potentials to explore the crossmodal links in spatial attention between vision and touch

2015

Colon E, Huang G, Legrain V, Mouraux A.

Journal of Cognitive Neuroscience

EEG frequency-tagging to dissociate the cortical responses to nociceptive and non-nociceptive stimuli

2014

Colon E, Legrain V, Mouraux A.

26(10):2262-74

Neurophysiologie Clinique - Clinical Neurophysiology

Steady-state evoked potentials to study the processing of tactile and nociceptive somatosensory input in the human brain

2012

Colon E, Legrain V, Mouraux A.

42(5):315-23

Neuroimage

Steady-state evoked potentials to tag specific components of nociceptive cortical processing

2011

Colon E, Nozaradan S, Legrain V, Mouraux A.

60(1):571-581

Journal of Neuroscience

Nociceptive steady-state evoked potentials elicited by rapid periodic thermal stimulation of cutaneous nociceptors

2011

Mouraux A, Iannetti GD, Colon E, Legrain V, Nozaradan S, Plaghki L.

31(16): 6079-87

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN