Role of the insula in nociception

A widely accepted notion is that one particular region of the “pain matrix”, the insula, plays a specific role in the perception of pain, and the activity recorded from this region is often considered as an objective signature of pain perception and its modulation.

Researchers involved

Publications

Neuroimage

Tonic thermonociceptive stimulation selectively modulates ongoing neural oscillations in the human posterior insula: evidence from intracerebral EEG

2018

Liberati G, Algoet M, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

188:70-83

Journal of Physiology

Deep continuous theta burst stimulation of the operculo-insular cortex selectively affects Adelta-fiber heat pain

2018

Lenoir C*, Algoet M*, Mouraux A.

596(19):4767-4787

Nature: Scientific Reports

Habituation of phase-locked local field potentials and gamma-band oscillations recorded from the human insula

2018

Liberati G, Algoet M, Klöcker A, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

8(1): 8265

Brain Stimulationation

Report of one confirmed generalized seizure and one suspected partial seizure induced by deep continuous theta burst stimulation of the right operculo-insular cortex

2018

Lenoir C*, Algoet M*, Vanderclausen C, Peeters A, Ferrao Santos S, Mouraux A.

11(5):1187-1188

Cerebral Cortex

Gamma-band oscillations preferential for nociception can be recorded in the human insula

2017

Liberati G, Klöcker A, Algoet M, Mulders D, Safronova MM, Ferrao Santos S, Vaz JG, Raftopoulos C, Mouraux A.

28(10):3650-3664.

PLoS Biology

Nociceptive local field potentials recorded from the human insula are not specific for nociception

2016

Liberati G, Klocker A, Safronova MM, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.

14(1):e1002345

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN