Pain-related oscillations

Nociceptive stimuli induce changes in the magnitude of oscillatory brain activity which is not phase locked, possible related to nociception or pain. This induced activity was found as a brief increase in gamma power in the 40-100 Hz frequency range, whose magnitude appears to correlate better with subjective pain intensity than the amplitude of phase-locked evoked potentials and could thus be a more specific marker for nociception. Besides gamma band oscillations (GBOs), nociceptive stimuli also induce changes in the magnitude of oscillations in other frequency bands, such as a suppression of alpha-band (7-13 Hz) and beta-band oscillations (13-30 Hz), a respective rebound of beta-band oscillations, and an increase in power of low-frequency delta oscillations (0-5 Hz).

Researchers involved

Publications

PLoS ONE

Dynamics of the perception and EEG signals triggered by tonic warm and cool stimulation

2020

Mulders D, de Bodt C, Lejeune N, Courtin A, Liberati G, Verleysen M, Mouraux A.

15(4):e0231698

Journal of Neurophysiology

Early gamma-oscillations as correlate of localized nociceptive processing in primary sensorimotor cortex

2020

Heid C, Mouraux A, Treede RD, Schuh-Hofer S, Rupp A, Baumgärtner U.

123(5):1711-1726

Neuroimage

Tonic thermonociceptive stimulation selectively modulates ongoing neural oscillations in the human posterior insula: evidence from intracerebral EEG

2018

Liberati G, Algoet M, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

188:70-83

Nature: Scientific Reports

Habituation of phase-locked local field potentials and gamma-band oscillations recorded from the human insula

2018

Liberati G, Algoet M, Klöcker A, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

8(1): 8265

Cerebral Cortex

Gamma-band oscillations preferential for nociception can be recorded in the human insula

2017

Liberati G, Klöcker A, Algoet M, Mulders D, Safronova MM, Ferrao Santos S, Vaz JG, Raftopoulos C, Mouraux A.

28(10):3650-3664.

Neuroimage

EEG frequency tagging using ultra-slow periodic heat stimulation of the skin reveals cortical activity specifically related to C fiber thermonociceptors

2016

Colon E, Liberati G, Mouraux A.

146:266-274

Neuroimage

Single-trial time-frequency analysis of electrocortical signals: baseline correction and beyond

2014

Hu L, Xiao P, Zhang ZG, Mouraux A, Iannetti GD.

84:876-8

Journal of Neuroscience

Gamma-band oscillations in the primary somatosensory cortex - a direct and obligatory correlate of subjective pain intensity

2012

Zhang ZG, Lu H, Hung YS, Mouraux A, Iannetti GD.

32(22): 7429-38

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN