Pain-related oscillations

Nociceptive stimuli induce changes in the magnitude of oscillatory brain activity which is not phase locked, possible related to nociception or pain. This induced activity was found as a brief increase in gamma power in the 40-100 Hz frequency range, whose magnitude appears to correlate better with subjective pain intensity than the amplitude of phase-locked evoked potentials and could thus be a more specific marker for nociception. Besides gamma band oscillations (GBOs), nociceptive stimuli also induce changes in the magnitude of oscillations in other frequency bands, such as a suppression of alpha-band (7-13 Hz) and beta-band oscillations (13-30 Hz), a respective rebound of beta-band oscillations, and an increase in power of low-frequency delta oscillations (0-5 Hz).

Researchers involved

Publications

2020

Insular responses to transient painful and non-painful thermal and mechanical spinothalamic stimuli recorded using intracerebral EEG

Nature: Scientific Reports

Liberati G, Mulders D, Algoet M, van den Broeke EN, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.

10: 22319

2020

Dynamics of the perception and EEG signals triggered by tonic warm and cool stimulation

PLoS ONE

Mulders D, de Bodt C, Lejeune N, Courtin A, Liberati G, Verleysen M, Mouraux A.

15(4):e0231698

2020

Early gamma-oscillations as correlate of localized nociceptive processing in primary sensorimotor cortex

Journal of Neurophysiology

Heid C, Mouraux A, Treede RD, Schuh-Hofer S, Rupp A, Baumgärtner U.

123(5):1711-1726

2018

Tonic thermonociceptive stimulation selectively modulates ongoing neural oscillations in the human posterior insula: evidence from intracerebral EEG

Neuroimage

Liberati G, Algoet M, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

188:70-83

2018

Habituation of phase-locked local field potentials and gamma-band oscillations recorded from the human insula

Nature: Scientific Reports

Liberati G, Algoet M, Klöcker A, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

8(1): 8265

2017

Gamma-band oscillations preferential for nociception can be recorded in the human insula

Cerebral Cortex

Liberati G, Klöcker A, Algoet M, Mulders D, Safronova MM, Ferrao Santos S, Vaz JG, Raftopoulos C, Mouraux A.

28(10):3650-3664.

2016

EEG frequency tagging using ultra-slow periodic heat stimulation of the skin reveals cortical activity specifically related to C fiber thermonociceptors

Neuroimage

Colon E, Liberati G, Mouraux A.

146:266-274

2014

Single-trial time-frequency analysis of electrocortical signals: baseline correction and beyond

Neuroimage

Hu L, Xiao P, Zhang ZG, Mouraux A, Iannetti GD.

84:876-8

2012

Gamma-band oscillations in the primary somatosensory cortex - a direct and obligatory correlate of subjective pain intensity

Journal of Neuroscience

Zhang ZG, Lu H, Hung YS, Mouraux A, Iannetti GD.

32(22): 7429-38

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN