Sabien van Neerven - former postdoc (UCL MoveIn)
The general objective of my project was to characterize the effects of topical capsaicin treatment on the changes in function and structure of nociceptive pathways associated with the development of chronic neuropathic pain and/or central sensitization. The project was translational, from bench to bedside, combining work performed in an animal model of neuropathic pain and work performed in patients suffering from chronic post-operative pain.
Publications
Frontiers in Pharmacology
van Neerven SGA, Mouraux A.
0.885416667
Capsaicin-induced skin desensitization differentially affects A-delta and C-fiber mediated heat sensitivity
2020
Journal of Neurophysiology
van den Broeke EN, Gousset S, Bouvy J, Stouffs A, Lebrun L, van Neerven SGA, Mouraux A.
122(3):994-1001
Heterosynaptic facilitation of mechanical nociceptive input is dependent on the frequency of conditioning stimulation
2019
Journal of Tissue Engineering and Regenerative Medicine
Boecker AH, Bozkurt A, Kim BS, Altinova H, Tank J, Deumens R, Tolba R, Weis J, Brook GA, Pallua N, van Neerven S.
12(11):2125-2137.
Cell-enrichment with olfactory ensheathing cells has limited local extra beneficial effects on nerve regeneration supported by the nerve guide Perimaix
2018
Journal of Neuroinflammation
Doyen PJ, Vergouts M, Pochet A, Desmet N, van Neerven S, Brook G, Hermans E.
14(1):209
Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain
2017
European Journal of Medical Research
Bozkurt A, Claeys KG, Schrading S, Rose JV, Sellhaus B, Schulz JB, Weis J, Pallua N and van Neerven S.
22(1): 34
Clinical and biometrical 12 months follow up study in patients after reconstruction of the sural nerve biopsy defect by the collagen-based nerve guide Neuromaix
2017
Journal of Tissue Engineering and Regenerative Medicine
Altinova H, Möllers S, Deumens R, Gerardo-Nava J, Führmann T, van Neerven S, Bozkurt A, Heschel I, Weis J, and Brook GA.
13(5): 585-600
Functional recovery not correlated with axon regeneration through OEC-seeded scaffolds in a model of acute SCI
2016
European Journal of Neuroscience
Boecker AH, van Neerven S, Scheffel J, Tank J, Altinova H, Seidensticker K, Deumens R, Tolba R, Weis J, Brook GA, Pallua N and Bozkurt A.
43(3): 404-16
Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model
2016
Biomaterials
Bozkurt A, Boecker A, Tank J, Altinova H, Deumens R, Dabhi C, Tolba R, Weis J, Brook GA, Pallua N, van Neerven SG.
75:112-22
Efficient bridging of 20 mm rat sciatic nerve lesions with a longitudinally micro-structured collagen scaffold
2016
Journal of Tissue Engineering and Regenerative Medicine
van Neerven SG, Haastert-Talini K, Boecker A, Schriever T, Dabhi C, Claeys K, Deumens R, Brook GA, Weis J, Pallua N, Bozkurt A.
Two-component collagen nerve guides support axonal regeneration in the rat peripheral nerve injury model
2016
European Journal of Neuroscience
Boecker AH, van Neerven SG, Scheffel J, Tank J, Altinova H, Seidensticker K, Deumens R, Tolba R, Weis J, Brook GA, Pallua N, Bozkurt A.
43(3):404-16
Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model
2016
BioMed Research International
van Neerven SG, Krings L, Haastert-Talini K, Vogt M, Tolba RH, Brook G, Pallua N, Bozkurt A.
2014:493823
Human Schwann cells seeded on a novel collagen-based microstructured nerve guide survive, proliferate, and modify neurite outgrowth
2014
BioMed Research International
Bozkurt A, van Neerven SG, Claeys KG, ODey DM, Sudhoff A, Brook GA, Sellhaus B, Schulz JB, Weis J, Pallua N.
2014:121452
The proximal medial sural nerve biopsy model: a standardised and reproducible baseline clinical model for the translational evaluation of bioengineered nerve guides
2014
Clinical Oral Implantations Research
Bozkurt A, Apel C, Sellhaus B, van Neerven S, Wessing B, Hilgers RD, Pallua N.
25(12):1403-11
Differences in degradation behavior of two non-cross-linked collagen barrier membranes: an in vitro and in vivo study
2014
Neuroscience
van Neerven SG, Pannaye P, Bozkurt A, Van Nieuwenhoven F, Joosten E, Hermans E, Taccola G, Deumens R.
252:144-53
Schwann cell migration and neurite outgrowth are influenced by media conditioned by epineurial fibroblasts
2013
Journal of Brachial Plexus and Peripheral Nerve Injury
van Neerven SG, Bozkurt A, ODey DM, Scheffel J, Boecker AH, Stromps JP, Dunda S, Brook GA, Pallua N.
7(1):5
Retrograde tracing and toe spreading after experimental autologous nerve transplantation and crush injury of the sciatic nerve: a descriptive methodological study
2012