Sabien van Neerven - former postdoc (UCL MoveIn)

The general objective of my project was to characterize the effects of topical capsaicin treatment on the changes in function and structure of nociceptive pathways associated with the development of chronic neuropathic pain and/or central sensitization. The project was translational, from bench to bedside, combining work performed in an animal model of neuropathic pain and work performed in patients suffering from chronic post-operative pain.

Publications

Frontiers in Pharmacology

van Neerven SGA, Mouraux A.

0.885416667

Capsaicin-induced skin desensitization differentially affects A-delta and C-fiber mediated heat sensitivity

2020

Journal of Neurophysiology

van den Broeke EN, Gousset S, Bouvy J, Stouffs A, Lebrun L, van Neerven SGA, Mouraux A.

122(3):994-1001

Heterosynaptic facilitation of mechanical nociceptive input is dependent on the frequency of conditioning stimulation

2019

Journal of Tissue Engineering and Regenerative Medicine

Boecker AH, Bozkurt A, Kim BS, Altinova H, Tank J, Deumens R, Tolba R, Weis J, Brook GA, Pallua N, van Neerven S.

in press

Cell-enrichment with olfactory ensheathing cells has limited local extra beneficial effects on nerve regeneration supported by the nerve guide Perimaix

2018

Journal of Neuroinflammation

Doyen PJ, Vergouts M, Pochet A, Desmet N, van Neerven S, Brook G, Hermans E.

14(1):209

Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain

2017

European Journal of Medical Research

Bozkurt A, Claeys KG, Schrading S, Rose JV, Sellhaus B, Schulz JB, Weis J, Pallua N and van Neerven S.

22(1): 34

Clinical and biometrical 12 months follow up study in patients after reconstruction of the sural nerve biopsy defect by the collagen-based nerve guide Neuromaix

2017

Journal of Tissue Engineering and Regenerative Medicine

Altinova H, Möllers S, Deumens R, Gerardo-Nava J, Führmann T, van Neerven S, Bozkurt A, Heschel I, Weis J, and Brook GA.

13(5): 585-600

Functional recovery not correlated with axon regeneration through OEC-seeded scaffolds in a model of acute SCI

2016

European Journal of Neuroscience

Boecker AH, van Neerven S, Scheffel J, Tank J, Altinova H, Seidensticker K, Deumens R, Tolba R, Weis J, Brook GA, Pallua N and Bozkurt A.

43(3): 404-16

Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model

2016

Biomaterials

Bozkurt A, Boecker A, Tank J, Altinova H, Deumens R, Dabhi C, Tolba R, Weis J, Brook GA, Pallua N, van Neerven SG.

75:112-22

Efficient bridging of 20 mm rat sciatic nerve lesions with a longitudinally micro-structured collagen scaffold

2016

Journal of Tissue Engineering and Regenerative Medicine

van Neerven SG, Haastert-Talini K, Boecker A, Schriever T, Dabhi C, Claeys K, Deumens R, Brook GA, Weis J, Pallua N, Bozkurt A.

Two-component collagen nerve guides support axonal regeneration in the rat peripheral nerve injury model

2016

European Journal of Neuroscience

Boecker AH, van Neerven SG, Scheffel J, Tank J, Altinova H, Seidensticker K, Deumens R, Tolba R, Weis J, Brook GA, Pallua N, Bozkurt A.

43(3):404-16

Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model

2016

BioMed Research International

van Neerven SG, Krings L, Haastert-Talini K, Vogt M, Tolba RH, Brook G, Pallua N, Bozkurt A.

2014:493823

Human Schwann cells seeded on a novel collagen-based microstructured nerve guide survive, proliferate, and modify neurite outgrowth

2014

BioMed Research International

Bozkurt A, van Neerven SG, Claeys KG, ODey DM, Sudhoff A, Brook GA, Sellhaus B, Schulz JB, Weis J, Pallua N.

2014:121452

The proximal medial sural nerve biopsy model: a standardised and reproducible baseline clinical model for the translational evaluation of bioengineered nerve guides

2014

Clinical Oral Implantations Research

Bozkurt A, Apel C, Sellhaus B, van Neerven S, Wessing B, Hilgers RD, Pallua N.

25(12):1403-11

Differences in degradation behavior of two non-cross-linked collagen barrier membranes: an in vitro and in vivo study

2014

Neuroscience

van Neerven SG, Pannaye P, Bozkurt A, Van Nieuwenhoven F, Joosten E, Hermans E, Taccola G, Deumens R.

252:144-53

Schwann cell migration and neurite outgrowth are influenced by media conditioned by epineurial fibroblasts

2013

Journal of Brachial Plexus and Peripheral Nerve Injury

van Neerven SG, Bozkurt A, ODey DM, Scheffel J, Boecker AH, Stromps JP, Dunda S, Brook GA, Pallua N.

7(1):5

Retrograde tracing and toe spreading after experimental autologous nerve transplantation and crush injury of the sciatic nerve: a descriptive methodological study

2012

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN