Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

NOCIONS : PAIN RESEARCH AT UCLOUVAIN

Emanuel van den Broeke

Postdoctorate researcher 

(FRC)

Group : André Mouraux

 

The main objective of my research is to study pain- or nociception-induced central nervous system plasticity. Currently, my studies are focused on characterizing changes in nociceptive pathways that lead or contribute to hyperalgesia, and I am, thereby, particularly interested in the phenomenon of "central sensitization"; the increase responsiveness of nociceptive neurons in the central nervous system that generates widespread hyperalgesia ("secondary hyperalgesia").

Giulia Liberati

Postdoctorate researcher 

(Chargé de recherches FNRS)

Group : André Mouraux

The main objective of my research is to characterize how transient and sustained pain are represented in the human brain, taking advantage of the high temporal and spatial resolution of intracerebral electroencephalography (iEEG). I am particularly interested in investigating the role of the human insula in nociception and pain perception, as several findings suggest that this brain region plays a crucial role in the integration of sensory, affective, and cognitive dimensions of pain.

Cédric Lenoir

Postdoctorate researcher at UCLondon (G.D. Iannetti)

Research collaborator at UCLouvain (A. Mouraux)

After a professional experience in the artistic field I worked as a physiotherapist notably in a chronic pain centre. From 2014-2018, I conducted a PhD at UCLouvain, under the supervision of André Mouraux and Samar Hatem, with the aim of characterizing the relationship and hierarchical organization between brain areas involved in nociceptive processing such as the primary somatosensory cortex and the operculo-insular cortex. I conducted several studies combining neuromodulation techniques (such as repetitive transcranial magnetic (rTMS) or transcranial and spinal direct current stimulation (tDCS)) combined with functional neuroimaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). I am also collaborating with Emanuel van den Broeke to a research project investigating central and peripheral mechanisms of secondary hyperalgesia. In 2019, I joined the research team of Prof. G.D. Iannetti (UCLondon).

Sabien van Neerven

Postdoctorate researcher 

(Move In Louvain)

Group : André Mouraux (+Emmanuel Hermans, IONS/CEMO)

The general objective of my project is to characterize the effects of topical capsaicin treatment on the changes in function and structure of nociceptive pathways associated with the development of chronic neuropathic pain and/or central sensitization. The proposed project is translational, from bench to bedside, as it will combine work performed in an animal model of neuropathic pain and work performed in patients suffering from chronic post-operative pain. 

Adriana Salatino

Postdoctorate researcher

(ARC GABA-AD + SAO/FRA).

Group :  André Mouraux (+ Adrian Ivanoiu, CUSL)

Lieve Filbrich

Postdoctorate researcher

(chargé de recherches FNRS).

Group: Valéry Legrain

Caroline Huart

Postdoctorate researcher 

(FNRS clinicien chercheur post-doctorant)

Group : André Mouraux (+ Philippe Rombaux, CUSL)

The aim of our research project is to develop new methods for assessing the function of the olfactory system in humans (psychophysical assessment and electrophysiological assessment using chemosensory event-related brain potentials (CSERP)). CSERPs have an important disadvantage: the relatively weak signal-to-noise ratio of the recorded responses often limit the interpretation of the recorded responses. We thus developed new stimulation and analysis techniques to increase the signal-to-noise ratio of olfactory and trigeminal CSERPs. Finally, we are documenting the usefulness of chemosensory assessment for the diagnosis of pathologies associated with olfactory dysfunction, in particular, the differential diagnosis of mild cognitive impairment. Clinician at the Dept. of Otorhinolaryngology of the Cliniques universitaires Saint Luc. 

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