André Mouraux - Principal investigator (IONS/COSY)

Using non-invasive functional neuroimaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), combined with novel techniques to selectively activate specific classes of nociceptive afferents, the research performed by the team of André Mouraux (IONS/COSY) follows two main axes. First, to understand how the human brain processes nociceptive sensory input and how this leads to the perception of pain. Second, to understand the plastic changes in nociceptive pathways that occur after inflammation, injury or sustained nociceptive input that induce peripheral and central sensitization and may underlie the development of chronic pain in humans.
Group members
Publications
2025
Electrical Spinal Imaging (ESI): Non invasive, high-resolution mapping of spinal cord activity
PLOS Biology
Gabrieli G, Somervail R, Mouraux A, Leandri M, Haggard P, Iannetti GD
in press
2025
Emerging role of electroencephalographic aperiodic activity in anesthesia: a narrative review
Anesthesiology
Demanet N, Khalifa C, Momeni M, Mouraux A, Lenoir C
in press
2025
Interindividual variations in peak alpha frequency do not predict the magnitude or extent of secondary hyperalgesia induced by high-frequency stimulation
J Neurophysiol
Lebrun L, Ricci G, Courtin A, van den Broeke EN, Lenoir C, Mouraux A
in press
2025
Effects of lacosamide, pregabalin, and tapentadol on peripheral nerve excitability: A randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects
Anesthesiology
Nochi Z, Pia H, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Fardo D, Genser B, Goetz M, Kostenko AV, Leone C, Li T, Jiang B, Rong C, Mouraux A, Pelz B, Phillips KG, Pogatzki-Zahn E, Schilder A, Schnetter E, Schubart K, Stouffs A, Tracey I, Troconiz IF, Truini A, Van Niel J, Vela JM, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Treede RD, Tankisi H, Finnerup NB
in press
2025
Boundaries of Tactile Acuity when Exploring Surfaces
Surface Topography: Metrology and Properties
Fradin J, Dione M, Mouraux A, Ackerley R, Gueorguiev D
in press
2025
Effect of Vagus Nerve Stimulation on Electroencephalogram Synchronization: A Longitudinal Study Using a Clinical-Research Response Scale
Neuromodulation
Danthine V, Germany Morrison EI, Cottin L, Liberati G, Cakiroglu I, Joris V, Mouraux A, Santalucia R, Fierain A, Vrielynck P, Santos SF, Nonclercq A, El Tahry R.
S1094-7159(25)00132-1.
2025
Strength, extent and duration of secondary hyperalgesia induced by high-frequency electrical stimulation of the foot compared to the volar forearm of healthy human volunteers
PLoS One
Lebrun L, Lenoir C, Leone C, van den Broeke EN, Caspani O, Schilder A, Pelz B, Truini A, Treede RD, Mouraux A
20(2):e0318934.
2025
A pain research strategy for Europe: A European survey and position paper of the European Pain Federation EFIC
Eur J Pain
Pickering G, O'Keeffe M, Bannister K, Becker S, Cottom S, Cox FJ, Eisenberg E, Finn DP, Forget P, Graven-Nielsen T, Kalso E, Kocot-Kepska M, Leite-Almeida H, Lopez-Garcia JA, Meeus M, Mouraux A, Pereira B, Puljak L, Reneman MF, Rohde I, Sotiropoulos I, Skidmore N, Tölle TR, Todorovic ST, Truini A, Vowles KE, Pogatzki-Zahn E, Garcia-Larrea L, Fullen BM
29(1):e4767.
