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André Mouraux - Principal investigator (IONS/COSY)

Group : 

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Using non-invasive functional neuroimaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), combined with novel techniques to selectively activate specific classes of nociceptive afferents, the research performed by the team of André Mouraux (IONS/COSY) follows two main axes. First, to understand how the human brain processes nociceptive sensory input and how this leads to the perception of pain. Second, to understand the plastic changes in nociceptive pathways that occur after inflammation, injury or sustained nociceptive input that induce peripheral and central sensitization and may underlie the development of chronic pain in humans.

Publications

2026

Aligned representation of visual and tactile motion directions in hMT+/V5 and fronto-parietal regions

Nature Communications

Shahzad I, Battal C, Cerpelloni F, Van Audenhaege A, Mouraux A, Collignon O

in press.

2026

Integration of auditory and tactile inputs to localize haptic stimuli during active touch

Atten Percept Psychophys

Esposito G, Courtin AS, Collignon O, Mouraux A

88(3):74.

2026

Complex regional pain syndrome evolution is determined by both biological and psychosocial factors: a 1-year prospective observational study

Pain

Louis MH, Legrain V, Aron V, Filbrich L, Mouraux A, Henrard S, Guillaume L, Mouraux D, Barbier O, Libouton X, Berquin A.

167(2):396-413.

2026

A multicentre randomized double-blind placebo-controlled study of lacosamide, pregabalin, and tapentadol on spinal pain biomarkers

Clin Neurophysiol

Leone CM, Di Pietro G, Di Stefano G, Quesada C, Salameh C, Perchet C, Garcia-Larrea L, Mouraux A, Lebrun L, Gousset S, Möller-Grell N, Kostenko A, Finnerup NB, Caspani O, Bo J, Genser B, Treede RD, Truini A

2111591.

2026

PDF

Extracting electroencephalogram aperiodic activity from intraoperative frontal α-band power does not modify its association with delirium after cardiac surgery

Eur J Anaesthesiol

Khalifa C, Momeni M, Renard A, Demanet N, Lenoir C, Mouraux A

43(4):362-365.

2026

Normative Values for Contact Heat and Cold Evoked Potentials

Eur J Pain

Foolchand Y, Kuzminova A, Louis MH, Courtin A, Dessart P, Mouraux A, Hatem SM

30(1):e70196.

2025

PDF

Global Poorer Olfaction, Frailty and Postoperative Adverse Outcomes: Exploring Their Interplay in a Prospective Cohort of Older Adults Undergoing Elective Surgery

Clin Interv Aging

Van Regemorter V, Momeni M, Bouhours J, Mouraux A, Huart C

20:2567-2578.

2025

Perceptual learning can improve nociceptive directional discrimination

Eur J Neurosci

Rujoie A, Andersen OK, Mouraux A, Frahm KS

62(11):e70350.

2025

Electrical Spinal Imaging (ESI): Non invasive, high-resolution mapping of spinal cord activity

PLOS Biology

Gabrieli G, Somervail R, Mouraux A, Leandri M, Haggard P, Iannetti GD

23(11):e3003116.

2025

Emerging role of electroencephalographic aperiodic activity in anesthesia: a narrative review

Anesthesiology

Demanet N, Khalifa C, Momeni M, Mouraux A, Lenoir C

144(2):473-480.

2025

Neural correlates underlying high-frequency stimulation-induced secondary hyperalgesia in humans

Pain Reports

Clarke S, Wanigasekera V, Rogers R, Caspani O, Mouraux A, Fardo F, Finnerup NB, Treede RD, Tracey I.

10(6):e1342.

2025

Interindividual variations in peak alpha frequency do not predict the magnitude or extent of secondary hyperalgesia induced by high-frequency stimulation

J Neurophysiol

Lebrun L, Ricci G, Courtin A, van den Broeke EN, Lenoir C, Mouraux A

134(6):1897-1911.

2025

Multisensory impact of visual stimuli on detection thresholds of thermo-nociceptive inputs conveyed by A-delta and C fibers

Behav Brain Res

Manfron L, Filbrich L, Della Porta D, Mouraux A, Legrain V.

496:115846.

2025

Effects of lacosamide, pregabalin, and tapentadol on peripheral nerve excitability: A randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects

Anesthesiology

Nochi Z, Pia H, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Fardo D, Genser B, Goetz M, Kostenko AV, Leone C, Li T, Jiang B, Rong C, Mouraux A, Pelz B, Phillips KG, Pogatzki-Zahn E, Schilder A, Schnetter E, Schubart K, Stouffs A, Tracey I, Troconiz IF, Truini A, Van Niel J, Vela JM, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Treede RD, Tankisi H, Finnerup NB

143(5):1279-1295.

2025

PDF

Boundaries of Tactile Acuity when Exploring Surfaces

Surface Topography: Metrology and Properties

Fradin J, Dione M, Mouraux A, Ackerley R, Gueorguiev D

13:033001

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

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