André Mouraux - Principal investigator (IONS/COSY)
Group :

Using non-invasive functional neuroimaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), combined with novel techniques to selectively activate specific classes of nociceptive afferents, the research performed by the team of André Mouraux (IONS/COSY) follows two main axes. First, to understand how the human brain processes nociceptive sensory input and how this leads to the perception of pain. Second, to understand the plastic changes in nociceptive pathways that occur after inflammation, injury or sustained nociceptive input that induce peripheral and central sensitization and may underlie the development of chronic pain in humans.
Publications
2026
A multicentre randomized double-blind placebo-controlled study of lacosamide, pregabalin, and tapentadol on spinal pain biomarkers
Clin Neurophysiol
Leone CM, Di Pietro G, Di Stefano G, Quesada C, Salameh C, Perchet C, Garcia-Larrea L, Mouraux A, Lebrun L, Gousset S, Möller-Grell N, Kostenko A, Finnerup NB, Caspani O, Bo J, Genser B, Treede RD, Truini A
2111591.
2026
Extracting electroencephalogram aperiodic activity from intraoperative frontal α-band power does not modify its association with delirium after cardiac surgery
Eur J Anaesthesiol
Khalifa C, Momeni M, Renard A, Demanet N, Lenoir C, Mouraux A
43(4):362-365.
2025
Global Poorer Olfaction, Frailty and Postoperative Adverse Outcomes: Exploring Their Interplay in a Prospective Cohort of Older Adults Undergoing Elective Surgery
Clin Interv Aging
Van Regemorter V, Momeni M, Bouhours J, Mouraux A, Huart C
20:2567-2578.
2025
Effects of lacosamide, pregabalin, and tapentadol on peripheral nerve excitability: A randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects
Anesthesiology
Nochi Z, Pia H, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Fardo D, Genser B, Goetz M, Kostenko AV, Leone C, Li T, Jiang B, Rong C, Mouraux A, Pelz B, Phillips KG, Pogatzki-Zahn E, Schilder A, Schnetter E, Schubart K, Stouffs A, Tracey I, Troconiz IF, Truini A, Van Niel J, Vela JM, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Treede RD, Tankisi H, Finnerup NB
143(5):1279-1295.
2025
Boundaries of Tactile Acuity when Exploring Surfaces
Surface Topography: Metrology and Properties
Fradin J, Dione M, Mouraux A, Ackerley R, Gueorguiev D
13:033001