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André Mouraux - Principal investigator (IONS/COSY)

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Using non-invasive functional neuroimaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), combined with novel techniques to selectively activate specific classes of nociceptive afferents, the research performed by the team of André Mouraux (IONS/COSY) follows two main axes. First, to understand how the human brain processes nociceptive sensory input and how this leads to the perception of pain. Second, to understand the plastic changes in nociceptive pathways that occur after inflammation, injury or sustained nociceptive input that induce peripheral and central sensitization and may underlie the development of chronic pain in humans.

Publications

2011

Parallel processing of nociceptive and non-nociceptive somatosensory information in the human primary and secondary somatosensory cortices: evidence from dynamic causal modelling of fMRI data

Journal of Neuroscience

Liang M, Mouraux A, Iannetti GD.

31(24): 8976-85

2011

Nociceptive steady-state evoked potentials elicited by rapid periodic thermal stimulation of cutaneous nociceptors

Journal of Neuroscience

Mouraux A, Iannetti GD, Colon E, Legrain V, Nozaradan S, Plaghki L.

31(16): 6079-87

2011

Can the fMRI responses to physical pain really tell us why social rejection "hurts"?

PNAS

Mouraux A, Iannetti GD.

108(30): E343

2011

Automated single-trial detection and quantification of evoked potentials, a potential tool for neuromonitoring?

Clinical Neurophysiology

Mouraux A, Guérit JM.

122(7): 1280-1

2011

Controlling attention to nociceptive stimuli with working memory

PLoS ONE

Legrain V, Crombez G, Mouraux A.

6(6): e20926

2011

The role of working memory in the attentional control of pain

Pain

Legrain V, Crombez G, Verhoeven K, Mouraux A.

152(2): 453-9

2011

Dishabituation of laser-evoked EEG responses: dissecting the effect of certain and uncertain changes in stimulus modality

Journal of Cognitive Neuroscience

Valentini E, Torta D, Mouraux A, Iannetti GD.

23(10):2822-37

2011

A multisensory investigation of the functional significance of the "pain matrix"

Neuroimage

Mouraux A, Diukova A, Lee MC, Wise RG, Iannetti GD.

54(3):2237-49

2011

The Pain Matrix Reloaded. A Salience Detection System for the Body

Progress in Neurobiology

Legrain V, Iannetti GD, Plaghki L, Mouraux A.

93(1); 111-124

2010

A novel approach for enhancing the signal-to-noise ratio and detecting automatically event-related potentials (ERPs) in single trials

Neuroimage

Hu L, Mouraux A, Hu Y, Iannetti GD.

50(1):99-111

2010

Low intensity intra-epidermal electrical stimulation can activate A-nociceptors selectively

Pain

Mouraux A, Iannetti GD, Plaghki L.

150 (1):199-207

2010

From the Neuromatrix to the Pain Matrix (and back)

Experimental Brain Research

Iannetti GD, Mouraux A.

205(1):1-12

2010

Stimulus novelty and not neural refractoriness explains the repetition suppression of laser-evoked potentials (LEPs)

Journal of Neurophysiology

Wang AL, Mouraux A, Liang M, Iannetti GD.

104(4):2116-24

2010

Functional characterisation of sensory ERPs using probabilistic ICA: effect of stimulus modality and stimulus location

Clinical Neurophysiology

Liang M, Mouraux A, Chan V, Blakemore C, Iannetti GD.

121(4):577-87

2009

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Usefulness and feasibility of psychophysical and electrophysiological olfactory testing in the rhinology clinic

Rhinology

Rombaux P, Mouraux A, Collet S, Eloy P, Bertrand B.

47(1):28-35

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

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NOCIONS : PAIN RESEARCH AT UCLOUVAIN

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