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Emanuel van den Broeke

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The main objective of my research was to study pain - or nociception- induced central nervous system plasticity. Currently, my studies are focused on characterizing changes in nociceptive pathways that lead or contribute to hyperalgesia, and I am, thereby, particularly interested in the phenomenon of "central sensitization"; the increase responsiveness of nociceptive neurons in the central nervous system that generates widespread hyperalgesia ("secondary hyperalgesia").

Group members

Publications

2015

Characterizing pinprick evoked brain potentials before and after experimentally-induced secondary hyperalgesia

Journal of Neurophysiology

van den Broeke E, Mouraux A, Groneberg A, Pfau D, Treede RD, Klein T.

114(5):2672-81

2014

Enhanced brain responses to C fiber input in the area of secondary hyperalgesia induced by high frequency electrical stimulation of the skin

Journal of Neurophysiology

van den Broeke EN, Mouraux A.

112(9):2059-66

2014

High frequency electrical stimulation of human skin induces heterotopical mechanical and heat hyperalgesia and enhanced responses to vibrotactile input

Journal of Neurophysiology

van den Broeke EN, Mouraux A.

111(8):1564-73

2013

Altered cortical responsiveness to pain stimuli after high frequency electrical stimulation of the skin in patients with persistent pain after inguinal hernia repair

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PLoS ONE

van den Broeke EN, Koeslag L, Arendsen LJ, Nienhuijs SW, Rosman C, van Rijn CM, Wilder-Smith OHG, van Goor H.

2013

Negative expectations facilitate mechanical hyperalgesia after high-frequency electrical stimulation of human skin

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European Journal of Pain

van den Broeke EN, Geene N, van Rijn CM, Wilder-Smith OH, Oosterman J.

2013

Patients with Persistent Pain after Breast Cancer Treatment Show Enhanced Alpha Activity in Spontaneous EEG

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Pain Medicine

van den Broeke EN, Wilder-Smith OH, van Goor H, Vissers KC, van Rijn CM.

2012

The effect of high-frequency conditioning stimulation of human skin on reported pain intensity and event-related potentials

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Journal of Neurophysiology

van den Broeke EN, van Heck CH, Ceelen LA, van Rijn CM, van Goor H, Wilder-Smith OH.

108(8): 2276-81

2012

Patients with persistent pain after breast cancer surgery show both delayed and enhanced cortical stimulus processing

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The Journal of Pain Res

van den Broeke EN, de Vries M, van Goor H, Vissers KC, van Rijn CM, Wilder-Smith OH.

5: 139-50

2011

Neural correlates of heterotopic facilitation induced after high frequency electrical stimulation of nociceptive pathways

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Molecular Pain

van den Broeke EN, van Heck CH, van Rijn CM, Wilder-Smith OH.

07:28

2010

Neurophysiological correlates of nociceptive heterosynaptic long-term potentiation in humans

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Journal of Neurophysiology

van den Broeke EN, van Rijn CM, Biurrun Manresa JA, Andersen OK, Arendt-Nielsen L, Wilder-Smith OH.

103(4): 2107-13

2022

Evidence for alterations to dynamic quantitative sensory tests in patients with chronic temporomandibular myalgia: A systematic review of observational studies with meta-analysis.

J Oral Rehabil

Cayrol T, Meeus M, Aron V, Gatto C, Mouraux A, Roussel NA, Sallaz L, van den Broeke EN, Pitance L.

49(6):654-670.

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

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NOCIONS : PAIN RESEARCH AT UCLOUVAIN

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