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Laser-evoked brain potentials (LEPs)

In 1975, Mor and Carmon introduced infrared laser stimulators as tools to explore nociception in humans. Allowing brief, synchronous, and selective activation of cutaneous Adelta- and C-fibre nociceptors, laser heat stimulators are now used extensively to study nociception in humans.

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Researchers involved

Publications

2013

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Theta burst stimulation applied over primary motor and somatosensory cortices produces analgesia unrelated to the changes in nociceptive event-related potentials

PLoS ONE

Torta D, Legrain V, Algoet M, Olivier E, Duqué J, Mouraux A.

20; 8(8): e73263

2013

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Psychophysical and electrophysiological evidence for nociceptive dysfunction in CRPS

Pain

Caty G, Hu L, Legrain V, Plaghki L, Mouraux A.

154(11):2521-8

2013

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Novelty is not enough: laser-evoked potentials are determined by stimulus saliency, not absolute novelty

Journal of Neurophysiology

Ronga I, Valentini E, Mouraux A, Iannetti GD.

109(3):692-701

2012

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Automated single-trial assessment of laser-evoked potentials as an objective functional diagnostic tool for the nociceptive system

Clinical Neurophysiology

Hatem SM, Hu L, Ragé M, Gierasimowicz-Fontana A, Plaghki L, Bouhassira D, Attal N, Iannetti GD, Mouraux A.

123(12): 2437-45

2012

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Dyspnea-pain counter-irritation induced by inspiratory threshold loading: a laser evoked potentials study

Journal of Applied Physiology

Bouvier G, La Violette L, Kindler F, Naccache L, Mouraux A, Similowski T, Morelot-Panzini C.

112(7):1166-73

2012

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Dishabituation of laser-evoked EEG responses: dissecting the effect of certain and uncertain changes in stimulus modality

Experimental Brain Research

Torta DM, Liang M, Valentini E, Mouraux A, Iannetti GD.

218(3): 361-72

2011

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Taking into account latency, amplitude and morphology: improved estimation of single-trial ERPs by wavelet filtering and multiple linear regression

Journal of Neurophysiology

Hu L, Liang M, Mouraux A, Wise RG, Hu Y, Iannetti GD.

106(6): 3216-29

2011

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Asymptomatic small fiber neuropathy in diabetes mellitus: investigations with intraepidermal nerve fiber density, quantitative sensory testing and laser-evoked potential

Journal of Neurology

Ragé M, Van Acker N, Knaapen MW, Timmers M, Streffer J, Hermans Mp, Sindic C, Meert T, Plaghki L.

258(10):1852-64

2011

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Dishabituation of laser-evoked EEG responses: dissecting the effect of certain and uncertain changes in stimulus modality

Journal of Cognitive Neuroscience

Valentini E, Torta D, Mouraux A, Iannetti GD.

23(10):2822-37

2010

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The time course of CO2 laser-evoked responses and of skin nerve fibre markers after topical capsaicin in human volunteers

Clinical Neurophysiology

Ragé M, Van Acker N, Facer P, Shenoy R, Knaapen MW, Timmers M, Streffer J, Anand P, Meert T, Plaghki L.

121(8):1256-66

2010

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A novel approach for enhancing the signal-to-noise ratio and detecting automatically event-related potentials (ERPs) in single trials

Neuroimage

Hu L, Mouraux A, Hu Y, Iannetti GD.

50(1):99-111

2010

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Clinical, functional and structural determinants of central pain in syringomyelia

Brain

Hatem SM, Attal N, Ducreux D, Gautron M, Parker F, Plaghki L, Bouhassira D.

133(11):3409-22

http://nocions.org

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

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NOCIONS : PAIN RESEARCH AT UCLOUVAIN

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