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Laser-evoked brain potentials (LEPs)

In 1975, Mor and Carmon introduced infrared laser stimulators as tools to explore nociception in humans. Allowing brief, synchronous, and selective activation of cutaneous Adelta- and C-fibre nociceptors, laser heat stimulators are now used extensively to study nociception in humans.

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Researchers involved

Publications

2005

Innocuous skin cooling modulates perception and neurophysiological correlates of brief CO2 laser stimuli in humans

European Journal of Pain

Nahra H, Plaghki L.

9(5):521-530

2005

Involuntary orientation of attention to unattended deviant nociceptive stimuli is modulated by concomitant visual task difficulty. Evidence from laser evoked potentials

Clinical Neurophysiology

Legrain V, Bruyer R, Guerit JM, Plaghki L.

116(9):2165-2174

2004

Single-trial detection of human brain responses evoked by laser activation of Adelta-nociceptors using the wavelet transform of EEG epochs

Neuroscience Letters

Mouraux A, Plaghki L.

361(1-3):241-244

2004

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Refractoriness cannot explain why C-fiber laser-evoked brain potentials are recorded only if concomitant Adelta-fiber activation is avoided

Pain

Mouraux A, Guerit JM, Plaghki L.

112(1-2):16-26

2003

Electrophysiological correlates of attentional orientation in humans to strong intensity deviant nociceptive stimuli, inside and outside the focus of spatial attention

Neuroscience Letters

Legrain V, Guerit JM, Bruyer R, Plaghki L.

339(2):107-110

2003

How do we selectively activate skin nociceptors with a high power infrared laser? Physiology and biophysics of laser stimulation

Neurophysiologie Clinique - Clinical Neurophysiology

Plaghki L, Mouraux A.

33(6):269-277

2003

Modulation of perception and neurophysiological correlates of brief CO2 laser stimuli in humans using concurrent large fiber stimulation

Somatosensory Motor Research

Nahra H, Plaghki L.

20(2):139-147

2003

The effects of A-fiber pressure block on perception and neurophysiological correlates of brief non-painful and painful CO2 laser stimuli in humans

European Journal of Pain

Nahra H, Plaghki L.

7(2):189-199

2003

Exogenous and endogenous components of ultralate (C-fibre) evoked potentials following CO2 laser stimuli to tiny skin surface areas in healthy subjects

Neurophysiologie Clinique - Clinical Neurophysiology

Opsommer E, Guerit JM, Plaghki L.

33(2):78-85

2003

Non-phase locked electroencephalogram (EEG) responses to CO2 laser skin stimulations may reflect central interactions between A(delta)- and C-fibre afferent volleys

Clinical Neurophysiology

Mouraux A, Guerit JM, Plaghki L.

114(4):710-722

2003

Nociceptive processing in the human brain of infrequent task-relevant and task-irrelevant noxious stimuli. A study with event-related potentials evoked by CO2 laser radiant heat stimuli

Pain

Legrain V, Bruyer R, Guerit JM, Plaghki L.

103(3):237-248

2002

Brain responses to signals ascending through C-fibers

International Congress Series

Plaghki L, Mouraux A.

K Hirata, editor, Vol. 1232. Amsterdam: Elsevier. pp. 181-192

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

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NOCIONS : PAIN RESEARCH AT UCLOUVAIN

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