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Infrared laser stimulation

In 1975, Mor and Carmon introduced infrared laser stimulators as tools to explore nociception in humans. Allowing brief, synchronous, and selective activation of cutaneous Adelta- and C-fibre nociceptors, laser heat stimulators are now used extensively to study nociception in humans. Recently, we have collaborated to the development of a novel CO2 laser stimulator whose power is regulated using a feedback control based on an online measurement of skin temperature at the site of stimulation (Laser Stimulation Device, SIFEC, Belgium).

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Researchers involved

Publications

2018

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Quickly-responding C-fiber nociceptors contribute to heat hypersensitivity in the area of secondary hyperalgesia

Journal of Physiology

Lenoir C, Plaghki L, Mouraux A, van den Broeke EN.

in press

2018

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Habituation of phase-locked local field potentials and gamma-band oscillations recorded from the human insula

Nature: Scientific Reports

Liberati G, Algoet M, Klöcker A, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

8(1): 8265

2015

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Characterizing pinprick evoked brain potentials before and after experimentally-induced secondary hyperalgesia

Journal of Neurophysiology

van den Broeke E, Mouraux A, Groneberg A, Pfau D, Treede RD, Klein T.

114(5):2672-81

2015

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Electrophysiological techniques to study the supraspinal responses to nociceptive input in humans

Pain persistence after surgery and altered central processing: science and clinical practice

Mouraux A.

Wilder-Smith OHG, Arendt-Nielsen L, Yarnitski D and Vissers K (Eds). IASP Press

2015

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Looking at the hand modulates the brain responses to nociceptive and non-nociceptive somatosensory stimuli but does not necessarily modulate their perception

Psychophysiology

Torta DM, Legrain V, Mouraux A.

52(8):1010-8

2014

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Enhanced brain responses to C fiber input in the area of secondary hyperalgesia induced by high frequency electrical stimulation of the skin

Journal of Neurophysiology

van den Broeke EN, Mouraux A.

112(9):2059-66

2014

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Short trains of intra-epidermal electrical stimulation to elicit reliable behavioral and electrophysiological responses to the selective activation of nociceptors in humans

Neuroscience Letters

Mouraux A, Marot E, Legrain V.

561: 69-73

2014

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Finite element analysis of thermal laser skin stimulation for a finer characterization of the nociceptive system

Journal of Neuroscience Methods

Marchandise E, Mouraux A, Plaghki L, Henrotte F.

223: 1-10

2013

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Capturing with EEG the neural entrainment and coupling underlying sensorimotor synchronization to the beat

Cerebral Cortex

Nozaradan S, Zerouali Y, Peretz I, Mouraux A.

25(3):736-47

2013

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Theta burst stimulation applied over primary motor and somatosensory cortices produces analgesia unrelated to the changes in nociceptive event-related potentials

PLoS ONE

Torta D, Legrain V, Algoet M, Olivier E, Duqué J, Mouraux A.

20; 8(8): e73263

http://nocions.org

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

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