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Infrared laser stimulation

In 1975, Mor and Carmon introduced infrared laser stimulators as tools to explore nociception in humans. Allowing brief, synchronous, and selective activation of cutaneous Adelta- and C-fibre nociceptors, laser heat stimulators are now used extensively to study nociception in humans. Recently, we have collaborated to the development of a novel CO2 laser stimulator whose power is regulated using a feedback control based on an online measurement of skin temperature at the site of stimulation (Laser Stimulation Device, SIFEC, Belgium).

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Researchers involved

Publications

2011

Asymptomatic small fiber neuropathy in diabetes mellitus: investigations with intraepidermal nerve fiber density, quantitative sensory testing and laser-evoked potential

Journal of Neurology

Ragé M, Van Acker N, Knaapen MW, Timmers M, Streffer J, Hermans Mp, Sindic C, Meert T, Plaghki L.

258(10):1852-64

2011

Dishabituation of laser-evoked EEG responses: dissecting the effect of certain and uncertain changes in stimulus modality

Journal of Cognitive Neuroscience

Valentini E, Torta D, Mouraux A, Iannetti GD.

23(10):2822-37

2010

The time course of CO2 laser-evoked responses and of skin nerve fibre markers after topical capsaicin in human volunteers

Clinical Neurophysiology

Ragé M, Van Acker N, Facer P, Shenoy R, Knaapen MW, Timmers M, Streffer J, Anand P, Meert T, Plaghki L.

121(8):1256-66

2010

A novel approach for enhancing the signal-to-noise ratio and detecting automatically event-related potentials (ERPs) in single trials

Neuroimage

Hu L, Mouraux A, Hu Y, Iannetti GD.

50(1):99-111

2010

Low intensity intra-epidermal electrical stimulation can activate A-nociceptors selectively

Pain

Mouraux A, Iannetti GD, Plaghki L.

150 (1):199-207

2010

Clinical, functional and structural determinants of central pain in syringomyelia

Brain

Hatem SM, Attal N, Ducreux D, Gautron M, Parker F, Plaghki L, Bouhassira D.

133(11):3409-22

2010

Stimulus novelty and not neural refractoriness explains the repetition suppression of laser-evoked potentials (LEPs)

Journal of Neurophysiology

Wang AL, Mouraux A, Liang M, Iannetti GD.

104(4):2116-24

2009

Nociceptive laser-evoked brain potentials do not reflect nociceptive-specific neural activity

Journal of Neurophysiology

Mouraux A, Iannetti GD.

101(6):3258-3269

2009

PDF

Are there nociceptive-specific brain potentials?

Journal of Neurophysiology

Mouraux A, Plaghki L, Iannetti GD.

102(5):3075-3076

2008

The enhancement of the N1 wave elicited by sensory stimuli presented at very short inter-stimulus intervals is a general feature across sensory systems

PLoS ONE

Wang AL, Mouraux A, Liang M, Iannetti GD.

3(12):e3929

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

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NOCIONS : PAIN RESEARCH AT UCLOUVAIN

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