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Giulia Liberati - Principal Investigator

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The main objective of my research is to characterize how transient and sustained pain are represented in the human brain, taking advantage of the high temporal and spatial resolution of intracerebral electroencephalography (iEEG). I am particularly interested in investigating the role of the human insula in nociception and pain perception, as several findings suggest that this brain region plays a crucial role in the integration of sensory, affective, and cognitive dimensions of pain.

Group members

Publications

2025

Commentary: From heterogeneity to precision - Mapping the future of rTMS for musculoskeletal pain

Br J Pain

Liberati G

20494637251391429. doi: 10.1177/20494637251391429.

2025

Individualised Alpha-tACS for Modulating Pain Perception and Neural Oscillations: A Sham-Controlled Study in Healthy Participants

PDF

Eur J Pain

Fathi Y, Dissassuca F, Ricci G, Liberati G.

29(7):e70086.

2025

Neural Correlates of taVNS: Scalp EEG and insular sEEG heartbeat evoked potentials modulation in an Epileptic patient case study

PDF

Clin Neurophysiol.

Germany Morrison E, Dumoulin M, Joris V, Santalucia R, Danthine V, Cakiroglu I, Liberati G, Nonclercq A, El Tahry R.

174:148-150.

2025

Effect of Vagus Nerve Stimulation on Electroencephalogram Synchronization: A Longitudinal Study Using a Clinical-Research Response Scale

PDF

Neuromodulation

Danthine V, Germany Morrison EI, Cottin L, Liberati G, Cakiroglu I, Joris V, Mouraux A, Santalucia R, Fierain A, Vrielynck P, Santos SF, Nonclercq A, El Tahry R.

S1094-7159(25)00132-1.

2025

The effect of stimulus saliency on the modulation of ongoing neural oscillations related to thermonociception: A registered report

PDF

Cortex

Leu C, Forest S, Legrain V, Liberati G.

185:316-335.

2025

Neural biomarkers of pain: defining perspectives and limitations of peak alpha frequency

PDF

Pain

Liberati G

166(9):1959-1960.

2024

Commentary : Advancements in noninvasive brain stimulation: exploring repetitive transcranial magnetic stimulation of the posterior superior insula for pain relief.

Pain

Liberati G.

in press

2024

Cue-based modulation of pain stimulus expectation: do ongoing oscillations reflect changes in pain perception? A registered report.

PDF

R Soc Open Sci

Leu C, Glineur E, Liberati G

11(6):240626.

2024

Electroencephalogram synchronization measure as a predictive biomarker of Vagus nerve stimulation response in refractory epilepsy: A retrospective study

PLoS One

Danthine V, Cottin L, Berger A, Germany Morrison EI, Liberati G, Ferrao Santos S, Delbeke J, Nonclercq A, El Tahry R

19(6):e0304115.

2024

Cue-based modulation of pain stimulus expectation: do ongoing oscillations reflect changes in pain perception? A registered report.

R Soc Open Sci

Leu C, Glineur E, Liberati G

11(6):240626.

2023

The role of ongoing oscillation in pain perception: Absence of modulation by a concomitant arithmetic task

Cortex

Leu C, Courtin A, Cussac C, Liberati G.

168:114-129.

2022

Characterization of vagus nerve stimulation-induced pupillary responses in epileptic patients

PDF

Brain Stimulation

Vespa S, Stumpp L, Liberati G, Delbeke J, Nonclercq A, Mouraux A, El Tahry R

in press.

2021

Vagus Nerve Stimulation elicits sleep EEG desynchronization and network changes in responder patients in epilepsy

Neurotherapeutics

Vespa S, Heyse J, Stumpp L, Liberati G, Ferrao Santos S, Rooijakkers H, Nonclercq A, Mouraux A, van Mierlo P, El Tahry R.

18(4):2623-2638.

2021

Transcutaneous auricular VNS applied to experimental pain: A paired behavioral and EEG study using thermonociceptive CO2 laser.

PLoS One

Dumoulin M, Liberati G, Mouraux A, Santos SF, El Tahry R.

16(7):e0254480.

2020

Insular responses to transient painful and non-painful thermal and mechanical spinothalamic stimuli recorded using intracerebral EEG

Nature: Scientific Reports

Liberati G, Mulders D, Algoet M, van den Broeke EN, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.

10: 22319

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

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NOCIONS : PAIN RESEARCH AT UCLOUVAIN

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